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506-32-1

506-32-1 structure
506-32-1 structure

Name arachidonic acid
Synonyms (5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic acid
AA
Immunocytophyte
eicosatetraenoic acid
MFCD00004417
PUFA 20:4n-6
ARACHIDONIC ACID(RG)
5,8,11,14-Icosatetraenoic Acid
Arachidonic acid
Hydrazinecarboselenoamide
ARA
5,8,11,14-Eicosatetraenoic Acid
(5Z,8Z,11Z,14Z)-5,8,11,14-Icosatetraenoic acid
C20:4 (cis-5,8,11,14)
20:4n-6
5,8,11,14-all-cis-Eicosatetraenoic acid
5,8,11,14-Eicosatetraenoic acid, (all-Z)-
5,8,11,14-Eicosatetraenoic acid, (5Z,8Z,11Z,14Z)-
Arachidonate
(5Z,8Z,11Z,14Z)-5,8,11,14-Eicosatetraenoic acid
Arachidonic
EINECS 208-033-4
(all-Z)-5,8,11,14-Eicosatetraenoic acid
Description Arachidonic acid is an essential fatty acid and a major constituent of biomembranes.
Related Catalog
Target

Human Endogenous Metabolite

In Vivo Arachidonic acid (ARA) is converted into various lipid mediators, such as prostaglandin E2 (PGE2), which is involved in the development of rheumatoid arthritis (RA)[1].
References

[1]. Tateishi N, et al. Dietary supplementation with arachidonic acid increases arachidonic acid content in paw, but does not affect arthritis severity or prostaglandin E2 content in rat adjuvant-induced arthritis model. Lipids Health Dis. 2015 Jan 16;14:3.

Density 0.9±0.1 g/cm3
Boiling Point 407.5±0.0 °C at 760 mmHg
Melting Point −49 °C(lit.)
Molecular Formula C20H32O2
Molecular Weight 304.467
Flash Point 336.3±18.0 °C
Exact Mass 304.240234
PSA 37.30000
LogP 6.91
Vapour Pressure 0.0±2.0 mmHg at 25°C
Index of Refraction 1.501
Water Solubility PRACTICALLY INSOLUBLE

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CE6675000
CHEMICAL NAME :
Arachidonic acid
CAS REGISTRY NUMBER :
506-32-1
LAST UPDATED :
199504
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C20-H32-O2
MOLECULAR WEIGHT :
304.52
WISWESSER LINE NOTATION :
QV4U3U3U3U6

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
39200 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
DOSE :
80 ug/kg
SEX/DURATION :
female 1 day(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - uterus, cervix, vagina

MUTATION DATA

TYPE OF TEST :
Sister chromatid exchange
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
320 umol/L
REFERENCE :
PAACA3 Proceedings of the American Association for Cancer Research. (Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1954- Volume(issue)/page/year: 27,95,1986 *** REVIEWS *** TOXICOLOGY REVIEW JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 12,481,1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T1132 No. of Facilities: 27 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 79 (estimated) No. of Female Employees: 60 (estimated)
Personal Protective Equipment Eyeshields;Faceshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
Hazard Codes F
Risk Phrases R19
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS CE6675000
Packaging Group I; II; III
Hazard Class 6.1
HS Code 2916190090
HS Code 2916190090
Summary 2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%