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1188-37-0

1188-37-0 structure
1188-37-0 structure

Name N-acetyl-L-glutamate(2-)
Synonyms (2S)-2-(acetylamino)pentanedioic acid
EINECS 214-708-4
N-Acetyl-L-glutamicacid
AC-GLU-OH
N-acetyl-L-glutamate
(S)-2-acetamidopentanedioic acid
N-ACETYL-L-GLU
N-AC-L-GLU
MFCD00002802
N-Acetyl-L-Glutamic
N-Acetyl-L-glutamic Acid
N-acetyl-Glu
acetylglutamicacid
Acetyl-L-glutamic acid
2-(acetylamino)pentanedioic acid
L-Glutamic acid, N-acetyl-
NAcGlu
n-acetylglutamic
N-Acetylglutamate
n-acetylglutamicacid
l-glutamicaci
Description N-Acetyl-L-glutamic acid, a N-acyl-L-amino acid, is a component of animal cell culturing media. N-Acetyl-L-glutamic acid is a metabolite of Saccharomyces cerevisiae and human[1].
Related Catalog
References

[1]. M Hashimoto, et al. Animal cell culturing media containing N-acetyl-L-glutamic acid. Patent.

Density 1.4±0.1 g/cm3
Boiling Point 495.9±35.0 °C at 760 mmHg
Melting Point 194-196 °C(lit.)
Molecular Formula C7H11NO5
Molecular Weight 189.166
Flash Point 253.7±25.9 °C
Exact Mass 189.063721
PSA 103.70000
LogP -2.24
Vapour Pressure 0.0±2.7 mmHg at 25°C
Index of Refraction 1.502
Storage condition 2~8°C
Water Solubility 2.7 g/100 mL (20 ºC)

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LZ9725000
CHEMICAL NAME :
L-Glutamic acid, N-acetyl-
CAS REGISTRY NUMBER :
1188-37-0
LAST UPDATED :
199701
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C7-H11-N-O5

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>7 gm/kg
TOXIC EFFECTS :
Brain and Coverings - changes in circulation (hemorrhage, thrombosis, etc.) Lungs, Thorax, or Respiration - other changes Blood - hemorrhage
REFERENCE :
TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (3),36,1995
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
6838 mg/kg
TOXIC EFFECTS :
Brain and Coverings - changes in circulation (hemorrhage, thrombosis, etc.) Lungs, Thorax, or Respiration - other changes Blood - hemorrhage
REFERENCE :
TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (3),36,1995
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
711 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (3),36,1995
Hazard Codes Xi
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 2
RTECS LZ9725000
HS Code 29241900

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1188-37-0 structure

1188-37-0

Literature: Veera Reddy; Ravindranath Synthetic Communications, 1992 , vol. 22, # 2 p. 257 - 264

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Literature: Journal of the American Chemical Society, , vol. 131, # 32 p. 11323 - 11325

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Literature: Chemische Berichte, , vol. 63, p. 438 Journal of Biological Chemistry, , vol. 132, p. 165

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1188-37-0 structure

1188-37-0

Literature: Journal of Physical Organic Chemistry, , vol. 25, # 11 p. 939 - 945

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1188-37-0 structure

1188-37-0

Literature: Journal of Physical Organic Chemistry, , vol. 25, # 11 p. 939 - 945

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1188-37-0 structure

1188-37-0

Literature: Journal of Physical Organic Chemistry, , vol. 25, # 11 p. 939 - 945

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Detail
Literature: Chemische Berichte, , vol. 63, p. 438 Journal of Biological Chemistry, , vol. 132, p. 165
HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%