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786593-06-4

786593-06-4 structure
786593-06-4 structure
  • Name: Dehydroandrographolide succinate
  • Chemical Name: 4-[[(1R,2R,4aS,5R,8aS)-2-(3-carboxypropanoyloxy)-1,4a-dimethyl-6-methylidene-5-[(2E)-2-(2-oxofuran-3-ylidene)ethyl]-3,4,5,7,8,8a-hexahydro-2H-naphthalen-1-yl]methoxy]-4-oxobutanoic acid
  • CAS Number: 786593-06-4
  • Molecular Formula: C28H36O10
  • Molecular Weight: 532.579
  • Catalog: analytical chemistry Standard Traditional Chinese medicine standard
  • Create Date: 2018-05-18 08:00:00
  • Modify Date: 2024-01-03 00:43:29
  • Dehydroandrographolide succinate, extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used for the treatment of viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect[1].

Name 4-[[(1R,2R,4aS,5R,8aS)-2-(3-carboxypropanoyloxy)-1,4a-dimethyl-6-methylidene-5-[(2E)-2-(2-oxofuran-3-ylidene)ethyl]-3,4,5,7,8,8a-hexahydro-2H-naphthalen-1-yl]methoxy]-4-oxobutanoic acid
Synonyms UNII-0X50BP49M1
Butanedioic acid, mono[[(1R,2R,4aR,5R,8aS)-2-(3-carboxy-1-oxopropoxy)-5-[(E)-2-(2,5-dihydro-2-oxo-3-furanyl)ethenyl]decahydro-1,4a-dimethyl-6-methylene-1-naphthalenyl]methyl] ester
4-({(1R,2R,4aR,5R,8aS)-2-[(3-Carboxypropanoyl)oxy]-1,4a-dimethyl-6-methylene-5-[(E)-2-(2-oxo-2,5-dihydro-3-furanyl)vinyl]decahydro-1-naphthalenyl}methoxy)-4-oxobutanoic acid
Dehydroandrographolide succinate
4-({(1R,2R,4aR,5R,8aS)-2-[(3-Carboxypropanoyl)oxy]-1,4a-dimethyl-6-methylene-5-[(E)-2-(2-oxo-2,5-dihydrofuran-3-yl)vinyl]decahydronaphthalen-1-yl}methoxy)-4-oxobutanoic acid
Description Dehydroandrographolide succinate, extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used for the treatment of viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect[1].
Related Catalog
References

[1]. Chen Q, et al. Pharmacokinetics and tolerance of dehydroandrographolide succinate injection after intravenousadministration in healthy Chinese volunteers. Acta Pharmacol Sin. 2012 Oct;33(10):1332-6.

Density 1.3±0.1 g/cm3
Boiling Point 733.8±60.0 °C at 760 mmHg
Melting Point 136-138ºC
Molecular Formula C28H36O10
Molecular Weight 532.579
Flash Point 239.1±26.4 °C
Exact Mass 532.230835
PSA 153.50000
LogP 2.85
Vapour Pressure 0.0±5.2 mmHg at 25°C
Index of Refraction 1.562
Hazard Codes Xi
Precursor  1

DownStream  0