Dehydroandrographolide succinate

Modify Date: 2024-01-03 00:43:29

Dehydroandrographolide succinate Structure
Dehydroandrographolide succinate structure
Common Name Dehydroandrographolide succinate
CAS Number 786593-06-4 Molecular Weight 532.579
Density 1.3±0.1 g/cm3 Boiling Point 733.8±60.0 °C at 760 mmHg
Molecular Formula C28H36O10 Melting Point 136-138ºC
MSDS N/A Flash Point 239.1±26.4 °C

 Use of Dehydroandrographolide succinate


Dehydroandrographolide succinate, extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used for the treatment of viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect[1].

 Names

Name 4-[[(1R,2R,4aS,5R,8aS)-2-(3-carboxypropanoyloxy)-1,4a-dimethyl-6-methylidene-5-[(2E)-2-(2-oxofuran-3-ylidene)ethyl]-3,4,5,7,8,8a-hexahydro-2H-naphthalen-1-yl]methoxy]-4-oxobutanoic acid
Synonym More Synonyms

 Dehydroandrographolide succinate Biological Activity

Description Dehydroandrographolide succinate, extracted from herbal medicine Andrographis paniculata (Burm f) Nees, is widely used for the treatment of viral pneumonia and viral upper respiratory tract infections because of its immunostimulatory, anti-infective and anti-inflammatory effect[1].
Related Catalog
References

[1]. Chen Q, et al. Pharmacokinetics and tolerance of dehydroandrographolide succinate injection after intravenousadministration in healthy Chinese volunteers. Acta Pharmacol Sin. 2012 Oct;33(10):1332-6.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 733.8±60.0 °C at 760 mmHg
Melting Point 136-138ºC
Molecular Formula C28H36O10
Molecular Weight 532.579
Flash Point 239.1±26.4 °C
Exact Mass 532.230835
PSA 153.50000
LogP 2.85
Vapour Pressure 0.0±5.2 mmHg at 25°C
Index of Refraction 1.562

 Safety Information

Hazard Codes Xi

 Precursor & DownStream

Precursor  1

DownStream  0

 Synonyms

UNII-0X50BP49M1
Butanedioic acid, mono[[(1R,2R,4aR,5R,8aS)-2-(3-carboxy-1-oxopropoxy)-5-[(E)-2-(2,5-dihydro-2-oxo-3-furanyl)ethenyl]decahydro-1,4a-dimethyl-6-methylene-1-naphthalenyl]methyl] ester
4-({(1R,2R,4aR,5R,8aS)-2-[(3-Carboxypropanoyl)oxy]-1,4a-dimethyl-6-methylene-5-[(E)-2-(2-oxo-2,5-dihydro-3-furanyl)vinyl]decahydro-1-naphthalenyl}methoxy)-4-oxobutanoic acid
Dehydroandrographolide succinate
4-({(1R,2R,4aR,5R,8aS)-2-[(3-Carboxypropanoyl)oxy]-1,4a-dimethyl-6-methylene-5-[(E)-2-(2-oxo-2,5-dihydrofuran-3-yl)vinyl]decahydronaphthalen-1-yl}methoxy)-4-oxobutanoic acid