Tos-PEG3
Modify Date: 2024-01-01 18:11:30
Tos-PEG3 structure
|
Common Name | Tos-PEG3 | ||
|---|---|---|---|---|
| CAS Number | 77544-68-4 | Molecular Weight | 304.35900 | |
| Density | 1.234±0.06 g/cm3 | Boiling Point | 460.0±35.0 °C | |
| Molecular Formula | C13H20O6S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Tos-PEG3Tos-PEG3 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Tos-PEG3 (structure 1) can be used for the synthesis of 3'-aminooxy oligonucleotides solid supports[1]. |
| Name | 2-[2-(2-Hydroxyethoxy)ethoxy]ethyl 4-methylbenzenesulfonate |
|---|---|
| Synonym | More Synonyms |
| Description | Tos-PEG3 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Tos-PEG3 (structure 1) can be used for the synthesis of 3'-aminooxy oligonucleotides solid supports[1]. |
|---|---|
| Related Catalog | |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
| References |
| Density | 1.234±0.06 g/cm3 |
|---|---|
| Boiling Point | 460.0±35.0 °C |
| Molecular Formula | C13H20O6S |
| Molecular Weight | 304.35900 |
| Exact Mass | 304.09800 |
| PSA | 90.44000 |
| LogP | 1.80660 |
| HS Code | 2909499000 |
|---|
|
~95%
Tos-PEG3 CAS#:77544-68-4 |
| Literature: Schmidt, Florian; Rosnizeck, Ina C.; Spoerner, Michael; Kalbitzer, Hans Robert; Koenig, Burkhard Inorganica Chimica Acta, 2011 , vol. 365, # 1 p. 38 - 48 |
|
~90%
Tos-PEG3 CAS#:77544-68-4 |
| Literature: Bouzide, Abderrahim; Sauve, Gilles Organic Letters, 2002 , vol. 4, # 14 p. 2329 - 2332 |
| Precursor 2 | |
|---|---|
| DownStream 10 | |
CAS#:17455-13-9
CAS#:2615-15-8
CAS#:208827-90-1
CAS#:3386-18-3![2-[2-(2-Aminoethoxy)ethoxy]ethanol structure](https://www.chemsrc.com/caspic/352/6338-55-2.png)
CAS#:6338-55-2
CAS#:139338-72-0![2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]acetic acid structure](https://www.chemsrc.com/caspic/007/172531-37-2.png)
CAS#:172531-37-2
CAS#:139115-92-7
CAS#:23978-55-4![2-[2-(2-fluoroethoxy)ethoxy]ethanol structure](https://www.chemsrc.com/caspic/227/373-45-5.png)
CAS#:373-45-5| HS Code | 2909499000 |
|---|---|
| Summary | 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0% |
| Ethanol,2-[2-(2-hydroxyethoxy)ethoxy]-,1-(4-methylbenzenesulfonate) |
| 2-(2-(2-Hydroxyethoxy)ethoxy)ethyl 4-methylbenzenesulfonate |
| triethyleneglycol monotosylate |
| 2,2'-[ethane-1,2-diylbis(oxy)]bis[ethanol] mono(4-methylbenzenesulfonate) |
| p-toluenesulfonic acid 2-(2-(2-hydroxyethoxy)ethoxy)ethoxy ester |
| Tos-PEG4 |
| HO(C2H4O)3Tos |
| toluene-4-sulfonic acid 2-[2-(2-hydroxy-ethoxy)ethoxy]ethyl ester |
| Ts(OCH2CH2)3OH |
| Tos-PEG3 |