Tosylate of Tetraethylene glycol monobenzyl ether
Modify Date: 2024-01-10 17:50:11
Tosylate of Tetraethylene glycol monobenzyl ether structure
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Common Name | Tosylate of Tetraethylene glycol monobenzyl ether | ||
|---|---|---|---|---|
| CAS Number | 89346-82-7 | Molecular Weight | 456.55000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H32O8S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Tosylate of Tetraethylene glycol monobenzyl etherBenzyl-PEG4-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
| Name | 4-methylbenzenesulfonic acid,2-[2-[2-(2-phenylmethoxyethoxy)ethoxy]ethoxy]ethanol |
|---|---|
| Synonym | More Synonyms |
| Description | Benzyl-PEG4-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. |
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| Related Catalog | |
| Target |
PEGs |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. |
| Molecular Formula | C22H32O8S |
|---|---|
| Molecular Weight | 456.55000 |
| Exact Mass | 456.18200 |
| PSA | 119.90000 |
| LogP | 3.56780 |
| Hazard Codes | Xi |
|---|
|
~10%
Tosylate of Tet... CAS#:89346-82-7 |
| Literature: WISCONSIN ALUMNI RESEARCH FOUNDATION Patent: WO2008/70490 A2, 2008 ; Location in patent: Page/Page column 33 ; |
|
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Tosylate of Tet... CAS#:89346-82-7 |
| Literature: Jain, Ahamindra; Huang, Shaw G.; Whitesides, George M. Journal of the American Chemical Society, 1994 , vol. 116, # 12 p. 5057 - 5062 |
|
~%
Tosylate of Tet... CAS#:89346-82-7 |
| Literature: Ahmed, Saleh A.; Tanaka, Mutsuo Journal of Organic Chemistry, 2006 , vol. 71, # 26 p. 9884 - 9886 |
|
~%
Tosylate of Tet... CAS#:89346-82-7 |
| Literature: Beadle, James R.; Korzeniowsky, Stephen H.; Rosenberg, David E.; Garcia-Slanga, Blanche J.; Gokel, George W. Journal of Organic Chemistry, 1984 , vol. 49, # 9 p. 1594 - 1603 |
| Precursor 5 | |
|---|---|
| DownStream 10 | |
![2-[2-[2-(2-phenoxyethoxy)ethoxy]ethoxy]ethanol structure](https://image.chemsrc.com/caspic/175/36366-93-5.png)
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CAS#:89346-83-8![2-nitrobenzoic acid,2-[2-[2-(2-phenoxyethoxy)ethoxy]ethoxy]ethanol structure](https://image.chemsrc.com/caspic/165/89346-84-9.png)
CAS#:89346-84-9![2-aminobenzoic acid,2-[2-[2-(2-phenoxyethoxy)ethoxy]ethoxy]ethanol structure](https://image.chemsrc.com/caspic/117/89346-85-0.png)
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| Tosylate of Tetraethylene glycol monobenzyl ether |