110026-03-4

110026-03-4 structure

Name: taurohyodeoxycholic acid sodium salt
Chemical Name: taurohyodeoxycholic acid sodium salt
CAS Number: 110026-03-4
Molecular Formula: C₂₆H₄₇NNaO₇S+
Molecular Weight: 540.71
Catalog: Signaling Pathways Apoptosis Apoptosis
Create Date: 2018-08-12 20:50:32
Modify Date: 2024-01-02 12:08:34
Taurodeoxychloic Acid (sodium hydrate) prevents apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation. Taurodeoxychloic Acid (sodium hydrate) is investigated for use in several conditions such as Primary Biliary Cirrhosis (PBC), insulin resistance, amyloidosis, Cystic Fibrosis, Cholestasis, and Amyotrophic Lateral Sclerosis[1].

Name	taurohyodeoxycholic acid sodium salt
Synonyms	SODIUM TAUROHYODEOXYCHOLATE Sodium taurohyodeoxycholate hydrate Sodium 2-{[(3α,5β,6α)-3,6-dihydroxy-24-oxocholan-24-yl]amino}ethanesulfonate Ethanesulfonic acid, 2-[[(3α,5β,6α)-3,6-dihydroxy-24-oxocholan-24-yl]amino]-, sodium salt (1:1) taurohyodeoxycholic acid sodium hydrate

Description	Taurodeoxychloic Acid (sodium hydrate) prevents apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation. Taurodeoxychloic Acid (sodium hydrate) is investigated for use in several conditions such as Primary Biliary Cirrhosis (PBC), insulin resistance, amyloidosis, Cystic Fibrosis, Cholestasis, and Amyotrophic Lateral Sclerosis[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Signaling Pathways >> Apoptosis >> Caspase Research Areas >> Inflammation/Immunology Research Areas >> Metabolic Disease
Target	Caspase-12
In Vivo	Taurodeoxychloic Acid (TUDCA) is neuroprotective in a transgenic animal model of Huntington’s disease[2].
References	[1]. Xie Q, et al. Effect of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation. Hepatology. 2002 Sep;36(3):592-601. [2]. Keene CD, et al. Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic animal model of Huntington's disease. Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10671-6.