taurohyodeoxycholic acid sodium salt

Modify Date: 2024-01-02 12:08:34

taurohyodeoxycholic acid sodium salt Structure
taurohyodeoxycholic acid sodium salt structure
Common Name taurohyodeoxycholic acid sodium salt
CAS Number 110026-03-4 Molecular Weight 540.71
Density N/A Boiling Point N/A
Molecular Formula C26H47NNaO7S+ Melting Point 168ºC (dec.)(lit.)
MSDS Chinese USA Flash Point N/A

 Use of taurohyodeoxycholic acid sodium salt


Taurodeoxychloic Acid (sodium hydrate) prevents apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation. Taurodeoxychloic Acid (sodium hydrate) is investigated for use in several conditions such as Primary Biliary Cirrhosis (PBC), insulin resistance, amyloidosis, Cystic Fibrosis, Cholestasis, and Amyotrophic Lateral Sclerosis[1].

 Names

Name taurohyodeoxycholic acid sodium salt
Synonym More Synonyms

 taurohyodeoxycholic acid sodium salt Biological Activity

Description Taurodeoxychloic Acid (sodium hydrate) prevents apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation. Taurodeoxychloic Acid (sodium hydrate) is investigated for use in several conditions such as Primary Biliary Cirrhosis (PBC), insulin resistance, amyloidosis, Cystic Fibrosis, Cholestasis, and Amyotrophic Lateral Sclerosis[1].
Related Catalog
Target

Caspase-12

In Vivo Taurodeoxychloic Acid (TUDCA) is neuroprotective in a transgenic animal model of Huntington’s disease[2].
References

[1]. Xie Q, et al. Effect of tauroursodeoxycholic acid on endoplasmic reticulum stress-induced caspase-12 activation. Hepatology. 2002 Sep;36(3):592-601.

[2]. Keene CD, et al. Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic animal model of Huntington's disease. Proc Natl Acad Sci U S A. 2002 Aug 6;99(16):10671-6.

 Chemical & Physical Properties

Melting Point 168ºC (dec.)(lit.)
Molecular Formula C26H47NNaO7S+
Molecular Weight 540.71
Exact Mass 521.278687
PSA 135.14000
LogP 4.52640
Storage condition 2-8℃

 Safety Information

Hazard Codes Xn: Harmful;
Risk Phrases 22-37
Safety Phrases 22-36
WGK Germany 3

 Synonyms

SODIUM TAUROHYODEOXYCHOLATE
Sodium taurohyodeoxycholate hydrate
Sodium 2-{[(3α,5β,6α)-3,6-dihydroxy-24-oxocholan-24-yl]amino}ethanesulfonate
Ethanesulfonic acid, 2-[[(3α,5β,6α)-3,6-dihydroxy-24-oxocholan-24-yl]amino]-, sodium salt (1:1)
taurohyodeoxycholic acid sodium hydrate
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