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107133-36-8

107133-36-8 structure
107133-36-8 structure
  • Name: Perindopril erbumine
  • Chemical Name: perindopril erbumine
  • CAS Number: 107133-36-8
  • Molecular Formula: C23H43N3O5
  • Molecular Weight: 441.605
  • Catalog: API Circulatory system medication Antihypertensive drug
  • Create Date: 2018-06-08 21:03:50
  • Modify Date: 2026-08-02 11:12:01
  • Perindopril erbumine is a potent ACE inhibitor of which is used to treat high blood pressure, heart failure or stable coronary artery disease.Target: ACEPerindopril is a long-acting ACE inhibitor. It is used to treat high blood pressure, heart failure or stable coronary artery disease in form of perindopril arginine (trade names include Coversyl, Coversum) or perindopril erbumine (trade name Aceon). According to the Australian government's Pharmaceutical Benefits Scheme website, based on data provided to the Australian Department of Health and Aging by the manufacturer, perindopril arginine and perindopril erbumine are therapeutically equivalent and may be interchanged without differences in clinical effect. However the dose prescribed to achieve the same effect will differ due to different molecular weights for the two forms. Perindopril is one of the most prescribed inhibitors of angiotensin converting enzyme, has a large evidence base, which allows to use it in patients with hypertension, diabetes mellitus type 2, coronary heart disease and chronic heart failure. In this review, the author focused on the evidence of organoprotecting properties of perindopril that lie outside lowering blood pressure.
Name perindopril erbumine
Synonyms Perindopril erbumine salt
S 9490-3
PrestariuM
(2S,3aS,7aS)-1-[(2S)-2-{[(1S)-1-(ethoxycarbonyl)butyl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acid - 2-methylpropan-2-amine (1:1) (non-preferred name)
Perindopril Impurity T(tert-Butylamine)
1-[2-(1-Ethoxycbonylbutylamino)propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-cboxylic acid 2-methyl-2-propanamine (1:1)
Perindopril for peak identification (Y0000771)
(6,9R,10-9-[(methylsulfonyl)methyl]-7-propyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline (pergolide sulfone)
Perinodpril ErbiMune
Perindopril t-ButylaMine
Perindopril erbumine //BP
Perindoril
Perindopril ErbumineQ: What is Perindopril Erbumine Q: What is the CAS Number of Perindopril Erbumine Q: What is the storage condition of Perindopril Erbumine
Perindopril for stereochemical purity CRS
(2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-Ethoxy-1-oxo-2-pentanyl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acid - 2-methyl-2-propanamine (1:1)
Perindopril tert-butylamine CRS
Perindopril t-Butylamine Salt
Perindopril Related Compound A (20 mg) ((2S,3aS,7aS)-octahydro-1H-indole-2-cboxylic acid)
(2S,3aS,7aS)-1-((S)-N-((S)-1-Carboxybutyl)alanyl)hexahydro-2-indolinecarboxylic Acid 1-Ethyl Ester compound with tert-Butylamine (1:1)
Procaptan
Unii-1964X464oj
Coversyl
(2S,3aS,7aS)-1-[(2S)-2-{[(1S)-1-(Ethoxycarbonyl)butyl]amino}propanoyl]octahydro-1H-indol-2-carbonsäure--2-methylpropan-2-amin(1:1)
Perindopril erbumine, 10 mM in DMSO
(2S-(1(R*(R*)),2a,3ab,7ab))-1-(2-((1-(Ethoxycarbonyl)butyl)amino)-1-oxopropyl)octahydro-1H-indole-2-carboxylic Acid compd. with 2-Methyl-2-propanamine (1:1)
Perinodopril
PrestiuM
(2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-cboxylic Acid 2-Methyl-2-propanaMine
Coversum
Perindopril t-Butylamine
Perindopril Impurity CC
Water-soluble tannalbin
Perindopril for stereochemical purity (Y0000207)
Aceon
2-Methylpropan-2-amine (2S,3aS,7aS)-1-((S)-2-(((S)-1-ethoxy-1-oxopentan-2-yl)amino)propanoyl)octahydro-1H-indole-2-cboxylate (Perindopril Impurity)
(2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-cboxylic acid tert-butylamine salt
Perindopril ErbuMine (Aceon)
(2S,3aS,7aS)-1-[(2S)-2-{[(2S)-1-Ethoxy-1-oxopentan-2-yl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acid - 2-methylpropan-2-amine (1:1) (non-preferred name)
acide (2S,3aS,7aS)-1-[(2S)-2-{[(1S)-1-(éthoxycarbonyl)butyl]amino}propanoyl]octahydro-1H-indole-2-carboxylique - 2-méthylpropan-2-amine (1:1)
McN-A 2833-109
Perindopril Erbumine (S-9490-3)
McN-A-2833-109
ButylaMiniperindopril
Perindopril Tables
Perindopril tert-butylamine salt
Perindopril Erbumine
CoversuM
Perindopril Impurity BB
Perindopril for peak identification CRS
MFCD02313824
Perindopril tert-butylamine
(2S,3aS,7aS)-1-[(2S)-2- {[(2S)-1-ethoxy-1-oxopentan-2- yl]amino}propanoyl]-octahydro-1H-indole-2- cboxylic acid 2-methylpropan-2-amine
Water-soluble tannic acid protein
prindopril API
PERINDOPRIL T-BUTYLAMINE SALT
2-Methylpropan-2-amine (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(ethoxycbonyl)butyl]amino]propanoyl]octahydro-1H-indole-2-cboxylate
S-9490-3
Perindopril t-butylamine salt - Bio-X
PERINDOPRIL TERT-BUTYLAMINE DRUG SUBSTANCE
Perindopril Impurity AA
(2S,3aS,7aS)-1-[(2S)-2-{[(1S)-1-(ethoxycarbonyl)butyl]amino}propanoyl]octahydro-1H-indole-2-carboxylic acid - 2-methylpropan-2-amine (1:1)
2-Methylpropan-2-amine (2S,3aS,7aS)-1-((S)-2-(((S)-1-ethoxy-1-oxopentan-2-yl)amino)propanoyl)octahydro-1H-indole-2-cboxylate
1H-Indole-2-cboxylic acid, 1-[(2S)-2-[[(1S)-1-(ethoxycbonyl)butyl]amino]-1-oxopropyl]octahydro-, (2S,3aS,7aS)-, compd. with 2-methyl-2-propanamine (1:1)
Pederindopril
Description Perindopril erbumine is a potent ACE inhibitor of which is used to treat high blood pressure, heart failure or stable coronary artery disease.Target: ACEPerindopril is a long-acting ACE inhibitor. It is used to treat high blood pressure, heart failure or stable coronary artery disease in form of perindopril arginine (trade names include Coversyl, Coversum) or perindopril erbumine (trade name Aceon). According to the Australian government's Pharmaceutical Benefits Scheme website, based on data provided to the Australian Department of Health and Aging by the manufacturer, perindopril arginine and perindopril erbumine are therapeutically equivalent and may be interchanged without differences in clinical effect. However the dose prescribed to achieve the same effect will differ due to different molecular weights for the two forms. Perindopril is one of the most prescribed inhibitors of angiotensin converting enzyme, has a large evidence base, which allows to use it in patients with hypertension, diabetes mellitus type 2, coronary heart disease and chronic heart failure. In this review, the author focused on the evidence of organoprotecting properties of perindopril that lie outside lowering blood pressure.
Related Catalog
References

[1]. Vaclavik J, Perindopril in the treatment of hypertension and cardiovascular diseases: evolution continues with the orodispersible dosage form. Vnitr Lek. 2013 Apr;59(4):290-4.

[2]. Napalkov DA. Therapy with perindopril: organoprotection, not just the antihypertensive effect. Kardiologiia. 2012;52(12):80-3.
Density 1.15 g/cm3
Boiling Point 537.4ºC at 760mmHg
Melting Point 126-128ºC
Molecular Formula C23H43N3O5
Molecular Weight 441.605
Flash Point 278.8ºC
Exact Mass 441.320282
PSA 121.96000
LogP 3.71330
Storage condition -20°C Freezer
Water Solubility H2O: soluble10mg/mL, clear
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases 26-36
RIDADR NONH for all modes of transport
RTECS NL5999600
82834-16-0 structure

82834-16-0

~95%

107133-36-8 structure

107133-36-8

Literature: Dubuffet, Thierry; Lecouve, Jean-Pierre Patent: US2007/43103 A1, 2007 ; Location in patent: Page/Page column 2 ;
1159491-00-5 structure

1159491-00-5

82834-12-6 structure

82834-12-6

75-64-9 structure

75-64-9

~62%

107133-36-8 structure

107133-36-8

Literature: KRKA, tovarna zdravil, d.d., Novo mesto Patent: EP1792896 A1, 2007 ; Location in patent: Page/Page column 7-8 ;
75-64-9 structure

75-64-9

~91%

107133-36-8 structure

107133-36-8

Literature: QUIMICA SINTETICA, S.A. Patent: WO2006/70276 A1, 2006 ; Location in patent: Page/Page column 8 ;
86647-57-6 structure

86647-57-6

82834-12-6 structure

82834-12-6

75-64-9 structure

75-64-9

~%

107133-36-8 structure

107133-36-8

Literature: WO2006/137082 A1, ; Page/Page column 11-12 ;
82834-16-0 structure

82834-16-0

75-64-9 structure

75-64-9

~94%

107133-36-8 structure

107133-36-8

Literature: Dubuffet, Thierry; Lecouve, Jean-Pierre Patent: US2006/178421 A1, 2006 ; Location in patent: Page/Page column 2 ;
200423-22-9 structure

200423-22-9

869877-95-2 structure

869877-95-2

75-64-9 structure

75-64-9

~%

107133-36-8 structure

107133-36-8

Literature: US2006/211867 A1, ; Page/Page column 4 ;
869877-95-2 structure

869877-95-2

80875-98-5 structure

80875-98-5

75-64-9 structure

75-64-9

~%

107133-36-8 structure

107133-36-8

Literature: US2006/211867 A1, ; Page/Page column 3-4 ;
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