Pimecrolimus hydrate
Modify Date: 2025-08-23 18:47:18
Pimecrolimus hydrate structure
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Common Name | Pimecrolimus hydrate | ||
|---|---|---|---|---|
| CAS Number | 1000802-56-1 | Molecular Weight | N/A | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C43H70ClNO12 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Pimecrolimus hydratePimecrolimus hydrate (SDZ-ASM 981 hydrate) is a potent, nonsteroid and orally active calcineurin inhibitor. Pimecrolimus hydrate shows anti-inflammatory activity. Pimecrolimus hydrate has the potential for the research of atopic dermatitis and oral erosive lichen planus[1][2][3]. |
| Name | Pimecrolimus hydrate |
|---|
| Description | Pimecrolimus hydrate (SDZ-ASM 981 hydrate) is a potent, nonsteroid and orally active calcineurin inhibitor. Pimecrolimus hydrate shows anti-inflammatory activity. Pimecrolimus hydrate has the potential for the research of atopic dermatitis and oral erosive lichen planus[1][2][3]. |
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| Related Catalog | |
| In Vitro | Pimecrolimus hydrate (100 nM) targets T-cells and mast cells and inhibits the production and release of cytokines and other inflammatory mediators, as well as the expression of signals essential for the activation of inflammatory T-lymphocytes[1]. |
| In Vivo | Pimecrolimus hydrate (10, 30 mg/kg; p.o.; daily for 4 weeks) increases in absolute numbers of T lymphocytes in KLH-immunised rats compared with non-immunised animals[2]. |
| References |
| Molecular Formula | C43H70ClNO12 |
|---|---|
| InChIKey | NZIZEODSJUZSHZ-MNZFELGNSA-N |
| SMILES | CCC1C=C(C)CC(C)CC(OC)C2OC(O)(C(=O)C(=O)N3CCCCC3C(=O)OC(C(C)=CC3CCC(Cl)C(OC)C3)C(C)C(O)CC1=O)C(C)CC2OC.O |