Acetyl Coenzyme A trisodium

Modify Date: 2025-08-21 17:41:04

Acetyl Coenzyme A trisodium structure	Common Name	Acetyl Coenzyme A trisodium
	CAS Number	102029-73-2	Molecular Weight	809.571
	Density	1.9±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₂₃H₃₈N₇O₁₇P₃S	Melting Point	N/A
	MSDS	USA	Flash Point	N/A

Use of Acetyl Coenzyme A trisodium

Acetyl Coenzyme A trisodium (Acetyl-CoA trisodium) is a central metabolic intermediate. Acetyl Coenzyme A trisodium is the actual molecule through which glycolytic pyruvate enters the tricarboxylic acid (TCA) cycle, is a key precursor of lipid synthesis, and is the sole donor of the acetyl groups for acetylation. Acetyl Coenzyme A trisodium acts as a potent allosteric activator of pyruvate carboxylase (PC)[1].

Name	Acetyl coenzyme A sodium salt
Synonym	More Synonyms

Description	Acetyl Coenzyme A trisodium (Acetyl-CoA trisodium) is a central metabolic intermediate. Acetyl Coenzyme A trisodium is the actual molecule through which glycolytic pyruvate enters the tricarboxylic acid (TCA) cycle, is a key precursor of lipid synthesis, and is the sole donor of the acetyl groups for acetylation. Acetyl Coenzyme A trisodium acts as a potent allosteric activator of pyruvate carboxylase (PC)[1].
Related Catalog	Research Areas >> Metabolic Disease
In Vitro	Acetyl-coenzyme A (Acetyl-CoA) is a membrane-impermeant molecule constituted by an acetyl moiety (CH3CO) linked to coenzyme A (CoA), a derivative of vitamin B5 and cysteine, through a thioester bond. As thioester bonds are energy rich, the chemical structure of acetyl-CoA facilitates the transfer of the acetyl moiety to a variety of acceptor molecules, including amino groups on proteins[1]. In most mammalian cells, Acetyl-coenzyme A (Acetyl-CoA) is predominantly generated in the mitochondrial matrix by various metabolic circuitries, namely glycolysis, β-oxidation, and the catabolism of branched amino acids. Cytosolic Acetyl-coenzyme A is the precursor of multiple anabolic reactions that underlie the synthesis of fatty acids and steroids, as well as specific amino acids including glutamate, proline, and arginine[1].
In Vivo	Mice deprived of food (but with access to water ad libitum) for 24 hr exhibit a significant reduction in total Acetyl-coenzyme A (Acetyl-CoA) levels in several organs, including the heart and muscles, corresponding to a decrease in protein acetylation levels. However, the same experimental conditions have no major effects on Acetyl-coenzyme A concentrations in the brain and actually increase hepatic Acetyl-coenzyme A and protein acetylation levels. Ethanol intake augments Acetyl-coenzyme A levels in hepatic mitochondria[1].
References	[1]. Federico Pietrocola, et al. Acetyl coenzyme A: a central metabolite and second messenger. Cell Metab. 2015 Jun 2;21(6):805-21.

Density	1.9±0.1 g/cm3
Molecular Formula	C₂₃H₃₈N₇O₁₇P₃S
Molecular Weight	809.571
Exact Mass	809.125793
PSA	418.36000
LogP	-3.89
Index of Refraction	1.718
Storage condition	-20 °C

Acetyl Coenzyme A trisodium MSDS(Chinese)

Personal Protective Equipment	Eyeshields;Faceshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Risk Phrases	R23/24/25
Safety Phrases	24-36/37-45
RIDADR	NONH for all modes of transport
WGK Germany	1

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Role of carnitine acetyltransferases in acetyl coenzyme A metabolism in Aspergillus nidulans.

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K-acetylation and its enzymes: overview and new developments.

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Lysine (K) acetylation refers to transfer of the acetyl moiety from acetyl-CoA to the ε-amino group of a lysine residue. This is posttranslational and reversible, with its level dynamically maintained...

ACETHYL COENZYME A SODIUM SALT

ACETYL COENZYME A (C2:0) SODIUMPREPARED ENZYMATICA

Adenosine, 5'-O-[[[[4-[[3-[[2-(acetylthio)ethyl]amino]-3-oxopropyl]amino]-3-hydroxy-2,2-dimethyl-4-oxobutoxy]hydroxyphosphinyl]oxy]hydroxyphosphinyl]-, 3'-(dihydrogen phosphate)

Acetyl-Coenzym A

acetyl coa

C2:0

S-{1-[(2R,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydro-2-furanyl]-3,5,9-trihydroxy-8,8-dimethyl-3,5-dioxido-10,14-dioxo-2,4,6-trioxa-11,15-diaza-3λ,5λ-dipho sphaheptadecan-17-yl} ethanethioate

Acetyl Coenzyme A Trisodium Salt

coenzyme A acetyl derivative (C2:0),sodium salt

Acetyl Coenzyme A

MFCD00078858