GSK 626616

Modify Date: 2025-08-24 18:54:29

GSK 626616 Structure
GSK 626616 structure
Common Name GSK 626616
CAS Number 1025821-33-3 Molecular Weight 401.269
Density 1.6±0.1 g/cm3 Boiling Point 574.8±60.0 °C at 760 mmHg
Molecular Formula C18H10Cl2N4OS Melting Point N/A
MSDS N/A Flash Point 301.4±32.9 °C

 Use of GSK 626616


GSK-626616 is a potent, orally bioavailable inhibitor of DYRK3 (IC50=0.7 nM). GSK-626616 inhibits other members of the DYRK family (e.g., DYRK1A and DYRK2) with similar potency, which is a potential therapy for the treatment of anemia[1].

 Names

Name GSK-626616
Synonym More Synonyms

 GSK 626616 Biological Activity

Description GSK-626616 is a potent, orally bioavailable inhibitor of DYRK3 (IC50=0.7 nM). GSK-626616 inhibits other members of the DYRK family (e.g., DYRK1A and DYRK2) with similar potency, which is a potential therapy for the treatment of anemia[1].
Related Catalog
Target

IC50: 0.7 nM (DYRK3)[1]

References

[1]. Connie L. Erickson-Miller, et al. GSK626616: A DYRK3 Inhibitor as a Potential New Therapy for the Treatment of Anemia. Blood 2007 110:510;

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 574.8±60.0 °C at 760 mmHg
Molecular Formula C18H10Cl2N4OS
Molecular Weight 401.269
Flash Point 301.4±32.9 °C
Exact Mass 399.995239
LogP 4.16
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.755
Storage condition 2-8°C

 Synonyms

GSK-626616
OKY0RM282V
(5Z)-2-[(2,6-Dichlorophenyl)amino]-5-(6-quinoxalinylmethylene)-1,3-thiazol-4(5H)-one
4(5H)-Thiazolone, 2-[(2,6-dichlorophenyl)amino]-5-(6-quinoxalinylmethylene)-, (5Z)-
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.