GSK-8573

Modify Date: 2024-01-13 17:45:54

GSK-8573 Structure
GSK-8573 structure
Common Name GSK-8573
CAS Number 1693766-04-9 Molecular Weight 323.386
Density 1.1±0.1 g/cm3 Boiling Point N/A
Molecular Formula C20H21NO3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of GSK-8573


GSK8573 (compound 23) is an inactive control compound for GSK2801. GSK8573 has binding activity to BRD9 with a Kd value of 1.04 μM and is inactive against BAZ2A/B and other bromodomain familiy[1].

 Names

Name 1-[1-(3-Methoxyphenyl)-7-propoxy-3-indolizinyl]ethanone
Synonym More Synonyms

 GSK-8573 Biological Activity

Description GSK8573 (compound 23) is an inactive control compound for GSK2801. GSK8573 has binding activity to BRD9 with a Kd value of 1.04 μM and is inactive against BAZ2A/B and other bromodomain familiy[1].
Related Catalog
Target

BRD9:1.04 μM (Kd)

References

[1]. Chen P, et al. Discovery and Characterization of GSK2801, a Selective Chemical Probe for the Bromodomains BAZ2A and BAZ2B. J Med Chem. 2016 Feb 25;59(4):1410-24.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Molecular Formula C20H21NO3
Molecular Weight 323.386
Exact Mass 323.152130
LogP 4.44
Index of Refraction 1.569
Storage condition -20℃

 Synonyms

Ethanone, 1-[1-(3-methoxyphenyl)-7-propoxy-3-indolizinyl]-
1-[1-(3-Methoxyphenyl)-7-propoxy-3-indolizinyl]ethanone
GSK-8573
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Price: ¥783/10 mM * 1 mL in DMSO

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