GSK-239512

Modify Date: 2024-01-12 12:44:48

GSK-239512 Structure
GSK-239512 structure
Common Name GSK-239512
CAS Number 720691-69-0 Molecular Weight 377.479
Density 1.2±0.1 g/cm3 Boiling Point 607.6±55.0 °C at 760 mmHg
Molecular Formula C23H27N3O2 Melting Point N/A
MSDS N/A Flash Point 321.3±31.5 °C

 Use of GSK-239512


GSK239512 is a potent and brain penetrated H3 receptor antagonist. GSK239512 can be used for the research of mild-to-moderate Alzheimer's disease (AD)[1].

 Names

Name GSK-239512
Synonym More Synonyms

 GSK-239512 Biological Activity

Description GSK239512 is a potent and brain penetrated H3 receptor antagonist. GSK239512 can be used for the research of mild-to-moderate Alzheimer's disease (AD)[1].
Related Catalog
Target

H3 receptor

References

[1]. Grove RA, et, al. A randomized, double-blind, placebo-controlled, 16-week study of the H3 receptor antagonist, GSK239512 as a monotherapy in subjects with mild-to-moderate Alzheimer's disease. Curr Alzheimer Res. 2014 Jan;11(1):47-58.  

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 607.6±55.0 °C at 760 mmHg
Molecular Formula C23H27N3O2
Molecular Weight 377.479
Flash Point 321.3±31.5 °C
Exact Mass 377.210327
LogP 2.94
Vapour Pressure 0.0±1.7 mmHg at 25°C
Index of Refraction 1.627
Storage condition 2-8°C

 Safety Information

Hazard Codes Xn
Risk Phrases 23-26-37
Safety Phrases 23-26-37

 Synonyms

2-Pyrrolidinone, 1-[6-[(3-cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-3-pyridinyl]-
MFCD27922168
GSK-239512
1-{6-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-3-pyridinyl}-2-pyrrolidinone