GSK-239512

Modify Date: 2024-01-12 12:44:48

GSK-239512 structure	Common Name	GSK-239512
	CAS Number	720691-69-0	Molecular Weight	377.479
	Density	1.2±0.1 g/cm3	Boiling Point	607.6±55.0 °C at 760 mmHg
	Molecular Formula	C₂₃H₂₇N₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	321.3±31.5 °C

Use of GSK-239512

GSK239512 is a potent and brain penetrated H3 receptor antagonist. GSK239512 can be used for the research of mild-to-moderate Alzheimer's disease (AD)[1].

Name	GSK-239512
Synonym	More Synonyms

Description	GSK239512 is a potent and brain penetrated H3 receptor antagonist. GSK239512 can be used for the research of mild-to-moderate Alzheimer's disease (AD)[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Histamine Receptor
Target	H3 receptor
References	[1]. Grove RA, et, al. A randomized, double-blind, placebo-controlled, 16-week study of the H3 receptor antagonist, GSK239512 as a monotherapy in subjects with mild-to-moderate Alzheimer's disease. Curr Alzheimer Res. 2014 Jan;11(1):47-58.

Density	1.2±0.1 g/cm3
Boiling Point	607.6±55.0 °C at 760 mmHg
Molecular Formula	C₂₃H₂₇N₃O₂
Molecular Weight	377.479
Flash Point	321.3±31.5 °C
Exact Mass	377.210327
LogP	2.94
Vapour Pressure	0.0±1.7 mmHg at 25°C
Index of Refraction	1.627
Storage condition	2-8°C

Hazard Codes	Xn
Risk Phrases	23-26-37
Safety Phrases	23-26-37

2-Pyrrolidinone, 1-[6-[(3-cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-3-pyridinyl]-

MFCD27922168

GSK-239512

1-{6-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-3-pyridinyl}-2-pyrrolidinone

GSK-239512

Use of GSK-239512

Names

GSK-239512 Biological Activity

Chemical & Physical Properties

Safety Information

Synonyms