Sepimostat dimethanesulfonate
Modify Date: 2024-01-08 10:38:09
Sepimostat dimethanesulfonate structure
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Common Name | Sepimostat dimethanesulfonate | ||
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| CAS Number | 103926-82-5 | Molecular Weight | 565.61900 | |
| Density | N/A | Boiling Point | 607.4ºC at 760mmHg | |
| Molecular Formula | C23H27N5O8S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 321.2ºC | |
Use of Sepimostat dimethanesulfonateSepimostat dimethanesulfonate (FUT-187) exhibits neuroprotective activity via NR2B N-methyl-D-aspartate receptor antagonism at the Ifenprodil-binding site of the NR2B subunit. Sepimostat dimethanesulfonate inhibits the Ifenprodil binding with a Ki value of 27.7 µM[1]. |
| Name | (6-methanehydrazonoylnaphthalen-2-yl) 4-(4,5-dihydro-1H-imidazol-2-ylamino)benzoate,methanesulfonic acid |
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| Synonym | More Synonyms |
| Description | Sepimostat dimethanesulfonate (FUT-187) exhibits neuroprotective activity via NR2B N-methyl-D-aspartate receptor antagonism at the Ifenprodil-binding site of the NR2B subunit. Sepimostat dimethanesulfonate inhibits the Ifenprodil binding with a Ki value of 27.7 µM[1]. |
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| Related Catalog | |
| In Vivo | Sepimostat (1 to 100 nmol/eye, intravitreal injection) exhibits significant neuroprotective effect[1]. Animal Model: Male Sprague Dawley rats weighing 150-300 g[1]. Dosage: Intravitreal injection. Administration: 1 to 100 nmol/eye. Result: Exhibited neuroprotective effects significantly. |
| References |
| Boiling Point | 607.4ºC at 760mmHg |
|---|---|
| Molecular Formula | C23H27N5O8S2 |
| Molecular Weight | 565.61900 |
| Flash Point | 321.2ºC |
| Exact Mass | 565.13000 |
| PSA | 238.09000 |
| LogP | 4.52120 |
| Vapour Pressure | 1.06E-14mmHg at 25°C |
| Storage condition | 2-8°C |
| 6-amidino-2-naphthyl 4-<(4,5-dihydro-1H-imidazol-2-yl)amino>benzoate methanesulfonate |
| 6-amidino-2-naphthyl 4-(2-imidazolinyl)amino-benzoate dimethanesulfonate |
| 6-Amidino-2-naphthyl 4-<(4,5-dihydro-1H-imidazol-2-yl)amino>benzoate dimethanesulfonate |
| 6a-methylhexahydro-2,6-methano-2H-cyclopenta<D>furan |
| 6'-amidino-2'-naphthyl-(4-(4,5-dihydro-1H-2-imidazolyl)amino)benzoate dimethanesulfonate |