Propionyl coenzyme A lithium
Propionyl coenzyme A lithium structure
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Common Name | Propionyl coenzyme A lithium | ||
|---|---|---|---|---|
| CAS Number | 108321-21-7 | Molecular Weight | 830.53800 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H40LiN7O17P3S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of Propionyl coenzyme A lithiumPropionyl coenzyme A lithium, a coenzyme A derivative of propionic acid, is an important metabolic intermediate formed by the thioester bond between coenzyme A and propionic acid. The breakdown and production of Propionyl coenzyme A lithim is important for the metabolism of organisms[1][2]. |
| Name | n-Propionyl coenzyme A lithium salt |
|---|---|
| Synonym | More Synonyms |
| Description | Propionyl coenzyme A lithium, a coenzyme A derivative of propionic acid, is an important metabolic intermediate formed by the thioester bond between coenzyme A and propionic acid. The breakdown and production of Propionyl coenzyme A lithim is important for the metabolism of organisms[1][2]. |
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| Related Catalog | |
| In Vitro | Propionyl coenzyme A lithium causes toxic effects due to its accumulation and the impact of its metabolism on cell wall synthesis and maintenance in Mycobacterium tuberculosis[1]. Propionyl coenzyme A lithium can be converted to β-hydroxypropionic acid via a peroxisomal enzyme-modified β-oxidation pathway in Arabidopsis[2]. Propionyl coenzyme A lithium causes the formation of propionic acidemia due to its abnormal accumulation, which often occurs in the neonatal developmental stage[3]. |
| References |
| Molecular Formula | C24H40LiN7O17P3S |
|---|---|
| Molecular Weight | 830.53800 |
| Exact Mass | 830.15700 |
| PSA | 425.34000 |
| LogP | 1.33650 |
| Storage condition | -20°C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P280-P305 + P351 + P338-P337 + P313 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi: Irritant; |
| Risk Phrases | 36/37/38 |
| Safety Phrases | 22-26-36 |
| RIDADR | NONH for all modes of transport |
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The Saccharomyces cerevisiae ICL2 gene encodes a mitochondrial 2-methylisocitrate lyase involved in propionyl-coenzyme A metabolism.
J. Bacteriol. 182 , 7007-7013, (2000) The Saccharomyces cerevisiae ICL1 gene encodes isocitrate lyase, an essential enzyme for growth on ethanol and acetate. Previous studies have demonstrated that the highly homologous ICL2 gene (YPR006c... |
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Gene acquisition, duplication and metabolic specification: the evolution of fungal methylisocitrate lyases.
Environ. Microbiol. 13 , 1534-1548, (2011) Gene duplication represents an evolutionary mechanism for expanding metabolic potential. Here we analysed the evolutionary relatedness of isocitrate and methylisocitrate lyases, which are key enzymes ... |
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The role of acyl-coenzyme A carboxylase complex in lipstatin biosynthesis of Streptomyces toxytricini.
Appl. Microbiol. Biotechnol. 87 , 1129-1139, (2010) Streptomyces toxytricini produces lipstatin, a specific inhibitor of pancreatic lipase, which is derived from two fatty acid moieties with eight and 14 carbon atoms. The pccB gene locus in 10.6 kb fra... |
| S-[2-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tet rahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphor yl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]ethyl ] propanethioate,lithium |