Epinastin HCl structure
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Common Name | Epinastin HCl | ||
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CAS Number | 108929-04-0 | Molecular Weight | 285.771 | |
Density | 1.32g/cm3 | Boiling Point | 428ºC at 760 mmHg | |
Molecular Formula | C16H16ClN3 | Melting Point | >270ºC | |
MSDS | Chinese USA | Flash Point | 212.7ºC | |
Symbol |
GHS06 |
Signal Word | Danger |
Use of Epinastin HClEpinastine hydrochloride (WAL801 hydrochloride) is an antihistamine and mast cell stabilizer. Epinastine hydrochloride is a potent, selective and orally-active histamine H1 receptor antagonist. Epinastine hydrochloride also inhibits IL-8 release and has an antiallergic action[1][2][3]. |
Name | Epinastine Hydrochloride |
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Synonym | More Synonyms |
Description | Epinastine hydrochloride (WAL801 hydrochloride) is an antihistamine and mast cell stabilizer. Epinastine hydrochloride is a potent, selective and orally-active histamine H1 receptor antagonist. Epinastine hydrochloride also inhibits IL-8 release and has an antiallergic action[1][2][3]. |
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Related Catalog | |
References |
Density | 1.32g/cm3 |
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Boiling Point | 428ºC at 760 mmHg |
Melting Point | >270ºC |
Molecular Formula | C16H16ClN3 |
Molecular Weight | 285.771 |
Flash Point | 212.7ºC |
Exact Mass | 285.103271 |
PSA | 41.62000 |
LogP | 3.46970 |
Vapour Pressure | 1.56E-07mmHg at 25°C |
Storage condition | 2-8°C |
Water Solubility | H2O: soluble38mg/mL |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
|
Symbol |
GHS06 |
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Signal Word | Danger |
Hazard Statements | H301 |
Precautionary Statements | P301 + P310 |
Personal Protective Equipment | Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges |
Hazard Codes | T: Toxic; |
Risk Phrases | R25 |
Safety Phrases | 45 |
RIDADR | UN 2811 6 |
RTECS | HO4360000 |
HS Code | 2933990090 |
~90% Epinastin HCl CAS#:108929-04-0 |
Literature: USV LIMITED Patent: WO2009/63504 A2, 2009 ; Location in patent: Page/Page column 25 ; |
~% Epinastin HCl CAS#:108929-04-0 |
Literature: Arzneimittel-Forschung/Drug Research, , vol. 40, # 4 p. 440 - 446 |
~% Epinastin HCl CAS#:108929-04-0 |
Literature: Arzneimittel-Forschung/Drug Research, , vol. 40, # 4 p. 440 - 446 |
~% Epinastin HCl CAS#:108929-04-0 |
Literature: Arzneimittel-Forschung/Drug Research, , vol. 40, # 4 p. 440 - 446 |
~% Epinastin HCl CAS#:108929-04-0 |
Literature: Arzneimittel-Forschung/Drug Research, , vol. 40, # 4 p. 440 - 446 |
HS Code | 2933990090 |
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Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Development and validation of an ultra-performance liquid chromatography method for simultaneous analysis of 20 antihistaminics in dietary supplements.
Biomed. Chromatogr. 29(3) , 465-74, (2015) The purpose of this study was to develop and validate an ultra-performance liquid chromatography method for simultaneous analysis of 20 antihistamines (illegal additives) in dietary supplements. The l... |
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Honey bee dopamine and octopamine receptors linked to intracellular calcium signaling have a close phylogenetic and pharmacological relationship.
PLoS ONE 6(11) , e26809, (2011) Three dopamine receptor genes have been identified that are highly conserved among arthropod species. One of these genes, referred to in honey bees as Amdop2, shows a close phylogenetic relationship t... |
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Differential effects of octopamine and tyramine on the central pattern generator for Manduca flight.
J. Comp. Physiol. A. Neuroethol. Sens. Neural. Behav. Physiol. 195(3) , 265-77, (2009) The biogenic amine, octopamine, modulates a variety of aspects of insect motor behavior, including direct action on the flight central pattern generator. A number of recent studies demonstrate that ty... |
9,13b-Dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepin-3-aminhydrochlorid |
UNII:GFM415S5XL |
9,13b-dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azépin-3-amine chlorhydrate |
9,13b-Dihydro-1H-dibenz[cf]imidazo[1,5-a]azepine hydrochloride,WAL-801Cl |
1H-Dibenz[c,f]imidazo[1,5-a]azepin-3-amine, 9,13b-dihydro-, hydrochloride (1:1) |
3-Amino-9,13b-dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepine Hydrochloride |
EPINASTINHCL |
Epinastine hydrochloride |
Epinastinehydrochloride |
1H-Dibenz[c,f]imidazo[1,5-a]azepin-3-amine,9,13b-dihydro-,hydrochloride |
T B5 G6&6 BN DN CUT&T&J CZ &&HCl |
EPIMEDIUM P.E |
EPINASTINE HCL |
Epinastine |
9,13b-dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepin-3-amine hydrochloride |
1H-DIBENZ[C,F]IMIDAZO[1,5-A]AZEPIN-3-AMINE,9,13B-DIHYDRO-, HYDROCHLORIDE (1:1) |
9,13b-Dihydro-1H-dibenzo[c,f]imidazo[1,5-a]azepin-3-amine hydrochloride (1:1) |
Epinastin HCl |