gamma-secretase modulator 2
Modify Date: 2024-01-03 18:09:18
gamma-secretase modulator 2 structure
|
Common Name | gamma-secretase modulator 2 | ||
|---|---|---|---|---|
| CAS Number | 1093978-89-2 | Molecular Weight | 514.47500 | |
| Density | 1.43 g/cm3 | Boiling Point | 729.8ºC at 760 mmHg | |
| Molecular Formula | C25H22F4N6O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 395.2ºC | |
Use of gamma-secretase modulator 2gamma-secretase modulator 2 is a potent and selective γ-secretase modulator for treatment of Alzheimer's diseaseIC50 value: Target: γ-secretaseγ-secretase modulator is modulation of the action of γ-secretase so as to Selectively attenuate production of Aβ(1-42) and hence find use in treatment or prevention of diseases associated with deposition of Aβ in the brain. γ-secretase modulator is usful in particular Alzheimer's disease. |
| Name | 6-fluoro-3-[4-[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]triazol-1-yl]-1-(2,2,2-trifluoroethyl)-4,5-dihydro-3H-1-benzazepin-2-one |
|---|---|
| Synonym | More Synonyms |
| Description | gamma-secretase modulator 2 is a potent and selective γ-secretase modulator for treatment of Alzheimer's diseaseIC50 value: Target: γ-secretaseγ-secretase modulator is modulation of the action of γ-secretase so as to Selectively attenuate production of Aβ(1-42) and hence find use in treatment or prevention of diseases associated with deposition of Aβ in the brain. γ-secretase modulator is usful in particular Alzheimer's disease. |
|---|---|
| Related Catalog |
| Density | 1.43 g/cm3 |
|---|---|
| Boiling Point | 729.8ºC at 760 mmHg |
| Molecular Formula | C25H22F4N6O2 |
| Molecular Weight | 514.47500 |
| Flash Point | 395.2ºC |
| Exact Mass | 514.17400 |
| PSA | 78.07000 |
| LogP | 4.73470 |
| Storage condition | 2-8℃ |
|
~%
gamma-secretase... CAS#:1093978-89-2 |
| Literature: WO2008/156580 A1, ; Page/Page column 43-44 ; WO 2008/156580 A1 |
![6-fluoro-3-(4-(3-Methoxy-4-(4-Methyl-1H-imidazol-1-yl)phenyl)-1H-1,2,3-triazol-1-yl)-4,5-dihydro-1H-benzo[b]azepin-2(3H)-one structure](https://image.chemsrc.com/caspic/438/1093978-67-6.png)
| Precursor 2 | |
|---|---|
| DownStream 0 | |
| 2H-1-Benzopyran-2-carbonitrile,6-fluoro-3,4-dihydro-4-oxo |
| 6-fluoro-3-{4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl}-1-(2,2,2-trifluoroethyl)-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one |
| 6-fluoro-3,4-dihydro-4-oxo-2H-1-benzopyran-2-carbonitrile |
| gamma-secretase modulator 2 |