L-Cysteinesulfinic acid
Modify Date: 2024-01-06 10:16:46
L-Cysteinesulfinic acid structure
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Common Name | L-Cysteinesulfinic acid | ||
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| CAS Number | 1115-65-7 | Molecular Weight | 153.16 | |
| Density | 1.828g/cm3 | Boiling Point | 492.8ºC at 760mmHg | |
| Molecular Formula | C3H7NO4S | Melting Point | >130°C (dec.) (lit.) | |
| MSDS | Chinese | Flash Point | 251.8ºC | |
Use of L-Cysteinesulfinic acidL-Cysteinesulfinic acid is a potent agonist at several rat metabotropic glutamate receptors (mGluRs) with pEC50s of 3.92±0.03, 4.6±0.2, 3.9±0.2, 2.7±0.2, 4.0±0.2, and 3.94±0.08 for mGluR1, mGluR5, mGluR2, mGluR4, mGluR6, and mGluR8, respectively. |
| Name | 3-sulfino-L-alanine |
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| Synonym | More Synonyms |
| Description | L-Cysteinesulfinic acid is a potent agonist at several rat metabotropic glutamate receptors (mGluRs) with pEC50s of 3.92±0.03, 4.6±0.2, 3.9±0.2, 2.7±0.2, 4.0±0.2, and 3.94±0.08 for mGluR1, mGluR5, mGluR2, mGluR4, mGluR6, and mGluR8, respectively. |
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| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| In Vitro | L-Cysteinesulfinic acid is an endogenous agonist of a metabotropic receptor coupled to stimulation of phospholipase D (PLD) activity. L-CSA is an endogenous agonist of the PLD-coupled metabotropic excitatory amino acids (EAA) receptor. L-CSA selectively activates the PLD-coupled receptor. 1 mM L-CSA induces a significant increase in PLD activity in hippocampal slices, whereas 1 mM concentrations of L-glutamate, L-aspartate, and L-HCA are without effect. L-CSA elicits a dose-dependent increase in PLD activity in rat hippocampal slices in the presence of iGluR antagonists, with an approximate EC50 of 500 uM. The PLD response induced by 1 mM L-CSA is not significantly decreased in the presence of 1 uM tetrodotoxin, suggesting that this response is not dependent upon L-CSA-induced increasesin cell firing[1]. |
| References |
| Density | 1.828g/cm3 |
|---|---|
| Boiling Point | 492.8ºC at 760mmHg |
| Melting Point | >130°C (dec.) (lit.) |
| Molecular Formula | C3H7NO4S |
| Molecular Weight | 153.16 |
| Flash Point | 251.8ºC |
| Exact Mass | 153.01000 |
| PSA | 119.83000 |
| LogP | 0.18600 |
| Vapour Pressure | 4.68E-11mmHg at 25°C |
| Index of Refraction | 1.673 |
| Hazard Codes | Xi: Irritant; |
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| Risk Phrases | 36/37/38 |
| Safety Phrases | 26-36 |
| HS Code | 2930909090 |
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L-Cysteinesulfi... CAS#:1115-65-7 |
| Literature: Hope,D.P. et al. Journal of the Chemical Society [Section] C: Organic, 1970 , p. 270 - 273 |
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L-Cysteinesulfi... CAS#:1115-65-7 |
| Literature: Perez-Benito, Joaquin F.; Arias, Conchita Journal of Physical Chemistry A, 1998 , vol. 102, # 29 p. 5837 - 5845 |
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L-Cysteinesulfi... CAS#:1115-65-7 |
| Literature: Mishra, Ritu; Mukhopadhyay, Subrata; Banerjee, Rupendranath Dalton Transactions, 2010 , vol. 39, # 10 p. 2692 - 2696 |
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L-Cysteinesulfi... CAS#:1115-65-7
Detail
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| Literature: Gottardi, Waldemar; Nagl, Markus Archiv der Pharmazie, 2002 , vol. 335, # 9 p. 411 - 421 |
CAS#:56-41-7
CAS#:300-84-5| HS Code | 2930909090 |
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| Summary | 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
| L-cysteine sulfinic acid |
| 2-amino-3-sulfino-propanoic acid |
| L-cysteine sulphinic acid |
| EINECS 214-228-5 |
| 3-sulphino-L-alanine |
| cysteinsulphinic acid |
| 3-Sulfinoalanine |
| L-CYSTEINESULFINIC ACID 1-HYDRATE |
| m-Chlorophenylbiguanide hydrochloride |
| 2-amino-3-sulfino-propionic acid |
| Cysteine sulphinic acid |
| L-Cysteinesulfinic acid |
| MFCD00044889 |