20(R)-Ginsenoside Rh2

Modify Date: 2025-08-21 17:56:46

20(R)-Ginsenoside Rh2 structure	Common Name	20(R)-Ginsenoside Rh2
	CAS Number	112246-15-8	Molecular Weight	622.873
	Density	1.19	Boiling Point	726.4±60.0 °C at 760 mmHg
	Molecular Formula	C₃₆H₆₂O₈	Melting Point	225 °C
	MSDS	N/A	Flash Point	393.1±32.9 °C

Use of 20(R)-Ginsenoside Rh2

20(R)-Ginsenoside Rh2, a matrix metalloproteinase (MMP) inhibitor, acts as a cell antiproliferator. It has anticancer effects via blocking cell proliferation and causing G1 phase arrest. 20(R)-Ginsenoside Rh2 induces apoptosis, and has anti-inflammatory and antioxidative activity[1][2][3].

Name	ginsenoside Rh2
Synonym	More Synonyms

Description	20(R)-Ginsenoside Rh2, a matrix metalloproteinase (MMP) inhibitor, acts as a cell antiproliferator. It has anticancer effects via blocking cell proliferation and causing G1 phase arrest. 20(R)-Ginsenoside Rh2 induces apoptosis, and has anti-inflammatory and antioxidative activity[1][2][3].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Research Areas >> Inflammation/Immunology Signaling Pathways >> Metabolic Enzyme/Protease >> MMP
References	[1]. Choi WY, et al. Anti-inflammatory, antioxidative and matrix metalloproteinase inhibitory properties of 20(R)-ginsenoside Rh2 in cultured macrophages and keratinocytes. J Pharm Pharmacol. 2013 Feb;65(2):310-6. [2]. Chung KS, et al. Ginsenoside Rh2 induces cell cycle arrest and differentiation in human leukemia cells by upregulating TGF-β expression. Carcinogenesis. 2013 Feb;34(2):331-40. [3]. Choi S, et al. Ginsenoside Rh2-mediated G1 phase cell cycle arrest in human breast cancer cells is caused by p15 Ink4B and p27 Kip1-dependent inhibition of cyclin-dependent kinases. Pharm Res. 2009 Oct;26(10):2280-8.

Description

Related Catalog

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Metabolic Enzyme/Protease >> MMP

References

[1]. Choi WY, et al. Anti-inflammatory, antioxidative and matrix metalloproteinase inhibitory properties of 20(R)-ginsenoside Rh2 in cultured macrophages and keratinocytes. J Pharm Pharmacol. 2013 Feb;65(2):310-6.

[2]. Chung KS, et al. Ginsenoside Rh2 induces cell cycle arrest and differentiation in human leukemia cells by upregulating TGF-β expression. Carcinogenesis. 2013 Feb;34(2):331-40.

[3]. Choi S, et al. Ginsenoside Rh2-mediated G1 phase cell cycle arrest in human breast cancer cells is caused by p15 Ink4B and p27 Kip1-dependent inhibition of cyclin-dependent kinases. Pharm Res. 2009 Oct;26(10):2280-8.

Density	1.19
Boiling Point	726.4±60.0 °C at 760 mmHg
Melting Point	225 °C
Molecular Formula	C₃₆H₆₂O₈
Molecular Weight	622.873
Flash Point	393.1±32.9 °C
Exact Mass	622.444458
PSA	139.84000
LogP	5.62
Vapour Pressure	0.0±5.4 mmHg at 25°C
Index of Refraction	1.572
InChIKey	CKUVNOCSBYYHIS-FJSBSAJOSA-N
SMILES	CC(C)=CCCC(C)(O)C1CCC2(C)C1C(O)CC1C3(C)CCC(OC4OC(CO)C(O)C(O)C4O)C(C)(C)C3CCC12C

12-O-acetyl-dam...

CAS#:127750-93-0

20(R)-Ginsenosi...

CAS#:112246-15-8

Literature: Atopkina, Lyubov N.; Uvarova, Nina I.; Elyakov, Georgi B. Carbohydrate Research, 1997 , vol. 303, # 4 p. 449 - 451

Precursor 1
CAS#:127750-93-0 12-O-acetyl-dam...
DownStream 0

Name: Toxicity in RANKL and TNFalpha-pretreated mouse RAW264 cells assessed as inhibition o...
Source: ChEMBL
Target: N/A
External Id: CHEMBL1787378

Name: Antioxidant activity assessed as DPPH radical scavenging activity at 1.6 mM after 20 ...
Source: ChEMBL
Target: N/A
External Id: CHEMBL1787377

Name: Inhibition of human recombinant aldose reductase using DL-glyceraldehyde, HRAR and be...
Source: ChEMBL
Target: Aldo-keto reductase family 1 member B1
External Id: CHEMBL3362499

Name: Inhibition of SIRT1 (unknown origin) assessed as reduction in Fluor de Lys deacetylat...
Source: ChEMBL
Target: NAD-dependent protein deacetylase sirtuin-1
External Id: CHEMBL4185127

Name: Fluorescence Mpro inhibition assay (S1) from Article : "Open science discovery of pot...
Source: BindingDB
Target: N/A
External Id: BindingDB_11549_3

Name: Toxicity in RANKL and TNFalpha-pretreated mouse RAW264 cells assessed as effect on ce...
Source: ChEMBL
Target: N/A
External Id: CHEMBL1787375

Total 6, Current Page 1 of 1

(3β,12β,20R)-12,20-Dihydroxydammar-24-en-3-yl β-D-glucopyranoside

20(R)-Ginsenoside Rh2

20(R)-Ginsenoside-Rh2

b-D-Glucopyranoside, (3b,12b,20R)-12,20-dihydroxydammar-24-en-3-yl

Ginsenoside-Rh2

(R) Ginsenoside Rh2

(3beta,12beta)-12,20-dihydroxydammar-24-en-3-yl beta-d-glucopyranoside

20-(R)-Ginsenoside Rh2

β-D-Glucopyranoside, (3β,12β,20R)-12,20-dihydroxydammar-24-en-3-yl

20(R)-GINSENOSIDERH2

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China
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China
Product Name: 20(R)-Ginsenoside Rh2
Price: ￥Inquiry/5mg ￥Inquiry/20mg ￥Inquiry/100mg ￥Inquiry/1g
Purity: 98.0%
Delivery: Inquiry
Contact: Bella
Email: 3157321941@qq.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 20(R)-Ginsenoside Rh2
Price: ￥788.0/20mg
Purity: 98.0%
Delivery: 2 Day
Contact: Liu jia
Email: 2130147988@qq.com

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20(R)-Ginsenoside Rh2

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20(R)-Ginsenoside Rh2 Biological Activity

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Precursor & DownStream

20(R)-Ginsenoside Rh2Bioassay

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.