HG-7-27-01
Modify Date: 2025-08-28 11:04:25
HG-7-27-01 structure
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Common Name | HG-7-27-01 | ||
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| CAS Number | 1135270-45-9 | Molecular Weight | 700.799 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 754.0±60.0 °C at 760 mmHg | |
| Molecular Formula | C37H43F3N10O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 409.8±32.9 °C | |
Use of HG-7-27-01HG-7-27-01 is a potent, selective c-Fes protein-tyrosine kinase inhibitor with IC50 of 224 nM, displays intermediate selectivity profiles (selectivity score=0.16) against 442 kinases. |
| Name | N-{4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl}-4-methyl-3-[(E)-2-(5-{[2-methyl-6-(1-piperazinyl)-4-pyrimidinyl]amino}-2-pyrazinyl)vinyl]benzamide |
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| Synonym | More Synonyms |
| Description | HG-7-27-01 is a potent, selective c-Fes protein-tyrosine kinase inhibitor with IC50 of 224 nM, displays intermediate selectivity profiles (selectivity score=0.16) against 442 kinases. |
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| References | References 1. Hellwig S, et al. Chem Biol. 2012 Apr 20;19(4):529-40. View Related Products by Target c-Fes Kinase |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 754.0±60.0 °C at 760 mmHg |
| Molecular Formula | C37H43F3N10O |
| Molecular Weight | 700.799 |
| Flash Point | 409.8±32.9 °C |
| Exact Mass | 700.357361 |
| LogP | 4.64 |
| Vapour Pressure | 0.0±2.5 mmHg at 25°C |
| Index of Refraction | 1.646 |
| N-{4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl}-4-methyl-3-[(E)-2-(5-{[2-methyl-6-(1-piperazinyl)-4-pyrimidinyl]amino}-2-pyrazinyl)vinyl]benzamide |
| Benzamide, N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[(E)-2-[5-[[2-methyl-6-(1-piperazinyl)-4-pyrimidinyl]amino]-2-pyrazinyl]ethenyl]- |