4-hydroxy-3-phenyl-naphthalene-1,2-dione

Modify Date: 2024-01-02 08:04:38

4-hydroxy-3-phenyl-naphthalene-1,2-dione structure	Common Name	4-hydroxy-3-phenyl-naphthalene-1,2-dione
	CAS Number	1150-59-0	Molecular Weight	250.24900
	Density	1.392g/cm3	Boiling Point	445.3ºC at 760 mmHg
	Molecular Formula	C₁₆H₁₀O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	237.2ºC

Use of 4-hydroxy-3-phenyl-naphthalene-1,2-dione

Antimalarial agent 14 (Compound N3) is a potent inhibitor of mitochondrial electron transport. Antimalarial agent 14 can serve as an anti-malarial agent[1].

Name	2-hydroxy-3-phenylnaphthalene-1,4-dione
Synonym	More Synonyms

Description	Antimalarial agent 14 (Compound N3) is a potent inhibitor of mitochondrial electron transport. Antimalarial agent 14 can serve as an anti-malarial agent[1].
Related Catalog	Research Areas >> Infection
Target	mitochondrial electron transport[1]
In Vitro	Antimalarial agent 14 (Compound N3) (0-400 μM, 48 h) inhibits P. falciparum with limited cytotoxicity against human cells[1]. Antimalarial agent 14 inhibits P. falciparum mitochondrial membrane potential with an IC50ΔΨmit of 16 μM[1]. Cell Cytotoxicity Assay[1] Cell Line: P. falciparum and HEK293T Concentration: 0.128, 0.64, 3.2, 16, 80 and 400 μM Incubation Time: 48 h Result: Showed inhibition with an IC50 of 443 nM against P. falciparum and showed cytotoxicity with a CC50 of 54.6 ± 0.23 μM.
References	[1]. Schuck DC, et al. Biological evaluation of hydroxynaphthoquinones as anti-malarials. Malar J. 2013 Jul 10;12:234.

Density	1.392g/cm3
Boiling Point	445.3ºC at 760 mmHg
Molecular Formula	C₁₆H₁₀O₃
Molecular Weight	250.24900
Flash Point	237.2ºC
Exact Mass	250.06300
PSA	54.37000
LogP	3.03490
Vapour Pressure	1.04E-08mmHg at 25°C
Index of Refraction	1.693
Storage condition	-20℃

Precursor 9
CAS#:98-80-6 Phenylboronic acid CAS#:51670-51-0 3-phenylnaphtha... CAS#:1681-79-4 3-BENZYLIDENEIS... CAS#:934-56-5 TRIMETHYL(PHENYL)TIN
CAS#:83-72-7 2-Hydroxy-1,4-n... CAS#:100-63-0 Phenylhydrazine CAS#:100-52-7 Benzaldehyde CAS#:2348-77-8 1,4-Naphthalene...
CAS#:5706-12-7 2-benzylidene-3...
DownStream 6
CAS#:83-12-5 Phenindione CAS#:106-34-3 Quinhydrone CAS#:51670-51-0 3-phenylnaphtha... CAS#:528-46-1 2-(Carboxycarbo...
CAS#:65-85-0 benzoic acid CAS#:88-99-3 Phthalic acid

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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 4-hydroxy-3-phenyl-naphthalene-1,2-dione
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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