TLR4-IN-C34-C2-COOH

Modify Date: 2024-01-10 10:54:25

TLR4-IN-C34-C2-COOH Structure
TLR4-IN-C34-C2-COOH structure
Common Name TLR4-IN-C34-C2-COOH
CAS Number 1159408-54-4 Molecular Weight 447.43
Density 1.29±0.1 g/cm3(Predicted) Boiling Point 634.1±55.0 °C(Predicted)
Molecular Formula C19H29NO11 Melting Point N/A
MSDS N/A Flash Point 337.3±31.5 °C

 Use of TLR4-IN-C34-C2-COOH


TLR4-IN-C34-C2-COO is a linker that incorporates TLR4 inhibitor TLR4-IN-C34. TLR4-IN-C34 inhibits TLR4 in enterocytes and macrophages, and reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis[1].

 Names

Name 5-[(3,4,6-Tri-O-acetyl-2-acetylamido-2-deoxy-b-D-galactopyranosyl)oxy]pentanoic acid
Synonym More Synonyms

 TLR4-IN-C34-C2-COOH Biological Activity

Description TLR4-IN-C34-C2-COO is a linker that incorporates TLR4 inhibitor TLR4-IN-C34. TLR4-IN-C34 inhibits TLR4 in enterocytes and macrophages, and reduces systemic inflammation in mouse models of endotoxemia and necrotizing enterocolitis[1].
Related Catalog
References

[1]. Neal MD, et al. Discovery and validation of a new class of small molecule Toll-like receptor 4 (TLR4) inhibitors. PLoS One. 2013;8(6):e65779. Published 2013 Jun 12.

 Chemical & Physical Properties

Density 1.29±0.1 g/cm3(Predicted)
Boiling Point 634.1±55.0 °C(Predicted)
Molecular Formula C19H29NO11
Molecular Weight 447.43
Flash Point 337.3±31.5 °C
Exact Mass 447.174072
LogP 0.27
Vapour Pressure 0.0±4.0 mmHg at 25°C
Index of Refraction 1.505
Storage condition Inert atmosphere,Store in freezer, under -20°C

 Safety Information

Hazard Codes Xi

 Synonyms

5-[(2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-galactopyranosyl)oxy]pentanoic acid
MFCD30802159
Pentanoic acid, 5-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-
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Price: ¥900/25 mg

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