PI3Kγ inhibitor 1
Modify Date: 2024-01-11 17:22:12
PI3Kγ inhibitor 1 structure
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Common Name | PI3Kγ inhibitor 1 | ||
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| CAS Number | 1172118-03-4 | Molecular Weight | 586.66600 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C32H26N8O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PI3Kγ inhibitor 1PI3Kγ inhibitor 1 is a PI3Kδ and PI3Kγ inhibitor extracted from patent WO2014004470A1, Compound 168 in Table 4, has IC50s of <100 nM. |
| Name | N-[6-[4-amino-1-[[8-methyl-2-(2-methylphenyl)-1-oxoisoquinolin-3-yl]methyl]pyrazolo[3,4-d]pyrimidin-3-yl]-1,3-benzothiazol-2-yl]acetamide |
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| Synonym | More Synonyms |
| Description | PI3Kγ inhibitor 1 is a PI3Kδ and PI3Kγ inhibitor extracted from patent WO2014004470A1, Compound 168 in Table 4, has IC50s of <100 nM. |
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| Related Catalog | |
| Target |
PI3Kδ:100 nM (IC50) PI3Kγ:100 nM (IC50) PI3Kα:10 μM (IC50) PI3Kβ:10 μM (IC50) |
| In Vitro | In Table 3, PI3Kγ inhibitor 1 (Compound 168) inhibits PI3Kδ, PI3Kγ, PI3Kα and PI3Kβ with IC50s of <100 nM, <100 nM, <10 μM and <10 μM, respectively. PI3Kγ inhibitor 1 inhibits B cell proliferation with an EC50<100 nM. |
| References |
| Molecular Formula | C32H26N8O2S |
|---|---|
| Molecular Weight | 586.66600 |
| Exact Mass | 586.19000 |
| PSA | 161.85000 |
| LogP | 6.26700 |
| PI3KGamma inhibitor 1 |
| PI3Kγ inhibitor 1 |