ERK Inhibitor II (Negative control)

Modify Date: 2024-01-11 20:28:20

ERK Inhibitor II (Negative control) structure	Common Name	ERK Inhibitor II (Negative control)
	CAS Number	1177970-73-8	Molecular Weight	328.32700
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₁₂N₆O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ERK Inhibitor II (Negative control)

ERK Inhibitor II (Negative control) is an effective inhibitor of extracellular signal-regulated kinase (ERK). ERK Inhibitor II (Negative control) inhibits the activation of insulin receptor, which can be used in the study of diabetes[1][2].

Name	5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-1,2-dihydropyrazolo[3,4-c]pyridazin-3-one
Synonym	More Synonyms

Description	ERK Inhibitor II (Negative control) is an effective inhibitor of extracellular signal-regulated kinase (ERK). ERK Inhibitor II (Negative control) inhibits the activation of insulin receptor, which can be used in the study of diabetes[1][2].
Related Catalog	Research Areas >> Metabolic Disease Signaling Pathways >> MAPK/ERK Pathway >> ERK Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Insulin Receptor Signaling Pathways >> Stem Cell/Wnt >> ERK
In Vitro	ERK Inhibitor II (Negative control) ( Irfin1) (10 µM) 抑制 CHO-K1 细胞中胰岛素诱导的胰岛素受体 (IR) 激活[2]。
References	[1]. Rezania A, et al. Differentiation of human embryonic stem cells to the pancreatic endocrine lineage. World Intellectual Property Organization. WO2010051223. [2]. Anastassiadis T, et al. A highly selective dual insulin receptor (IR)/insulin-like growth factor 1 receptor (IGF-1R) inhibitor derived from an extracellular signal-regulated kinase (ERK) inhibitor. J Biol Chem. 2013 Sep 27;288(39):28068-77.

Molecular Formula	C₁₈H₁₂N₆O
Molecular Weight	328.32700
Exact Mass	328.10700
PSA	91.99000
LogP	3.04020

HMS3229G08

ERK Inhibitor II,Negative Control

ERK Inhibitor II (Negative control)

Use of ERK Inhibitor II (Negative control)

Names

ERK Inhibitor II (Negative control) Biological Activity

Chemical & Physical Properties

Synonyms