ERK Inhibitor II (Negative control)

Modify Date: 2024-01-11 20:28:20

ERK Inhibitor II (Negative control) Structure
ERK Inhibitor II (Negative control) structure
Common Name ERK Inhibitor II (Negative control)
CAS Number 1177970-73-8 Molecular Weight 328.32700
Density N/A Boiling Point N/A
Molecular Formula C18H12N6O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ERK Inhibitor II (Negative control)


ERK Inhibitor II (Negative control) is an effective inhibitor of extracellular signal-regulated kinase (ERK). ERK Inhibitor II (Negative control) inhibits the activation of insulin receptor, which can be used in the study of diabetes[1][2].

 Names

Name 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-1,2-dihydropyrazolo[3,4-c]pyridazin-3-one
Synonym More Synonyms

 ERK Inhibitor II (Negative control) Biological Activity

Description ERK Inhibitor II (Negative control) is an effective inhibitor of extracellular signal-regulated kinase (ERK). ERK Inhibitor II (Negative control) inhibits the activation of insulin receptor, which can be used in the study of diabetes[1][2].
Related Catalog
In Vitro ERK Inhibitor II (Negative control) ( Irfin1) (10 µM) 抑制 CHO-K1 细胞中胰岛素诱导的胰岛素受体 (IR) 激活[2]。
References

[1]. Rezania A, et al. Differentiation of human embryonic stem cells to the pancreatic endocrine lineage. World Intellectual Property Organization. WO2010051223.

[2]. Anastassiadis T, et al. A highly selective dual insulin receptor (IR)/insulin-like growth factor 1 receptor (IGF-1R) inhibitor derived from an extracellular signal-regulated kinase (ERK) inhibitor. J Biol Chem. 2013 Sep 27;288(39):28068-77.  

 Chemical & Physical Properties

Molecular Formula C18H12N6O
Molecular Weight 328.32700
Exact Mass 328.10700
PSA 91.99000
LogP 3.04020

 Synonyms

HMS3229G08
ERK Inhibitor II,Negative Control
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