Vonafexor(PLX007,EYP-001)

Modify Date: 2025-08-26 17:03:01

Vonafexor(PLX007,EYP-001) structure	Common Name	Vonafexor(PLX007,EYP-001)
	CAS Number	1192171-69-9	Molecular Weight	489.76
	Density	1.604±0.06 g/cm3(Predicted)	Boiling Point	680.5±65.0 °C(Predicted)
	Molecular Formula	C₁₉H₁₅Cl₃N₂O₅S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Vonafexor(PLX007,EYP-001)

Vonafexor (EYP001) is a selective FXR agonist with anti-HBV effects[1][2].

Name	Vonafexor

Description

Vonafexor (EYP001) is a selective FXR agonist with anti-HBV effects[1][2].

Related Catalog

Research Areas >> Infection

Signaling Pathways >> Metabolic Enzyme/Protease >> FXR

Signaling Pathways >> Anti-infection >> HBV

References

[1]. Joly S, et al. The selective FXR agonist EYP001 is well tolerated in healthy subjects and has additive anti-HBV effect with nucleoside analogues in HepaRG cells. J Hepatol 66(1):S690.

[2]. Fiorucci S,et al. Bile acid modulators for the treatment of nonalcoholic steatohepatitis (NASH) [published online ahead of print, 2020 Jun 19]. Expert Opin Investig Drugs. 2020;1-10.

Density	1.604±0.06 g/cm3(Predicted)
Boiling Point	680.5±65.0 °C(Predicted)
Molecular Formula	C₁₉H₁₅Cl₃N₂O₅S
Molecular Weight	489.76

Hazard Codes	Xn

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China
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