UCN-02

Modify Date: 2024-01-25 00:05:17

UCN-02 structure	Common Name	UCN-02
	CAS Number	121569-61-7	Molecular Weight	482.537
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₈H₂₆N₄O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of UCN-02

UCN-02 (7-epi-Hydroxystaurosporine) is a selective protein kinase C (PKC) inhibitor produced by Streptomyces strain N-12, with IC50s of 62 nM and 250 nM for PKC and protein kinase A (PKA), respectively. UCN-02 (7-epi-Hydroxystaurosporine) displays cytotoxic effect on the growth of HeLa S3 cells[1][2].

Name	ANTIBIOTIC UCN-02

Description	UCN-02 (7-epi-Hydroxystaurosporine) is a selective protein kinase C (PKC) inhibitor produced by Streptomyces strain N-12, with IC50s of 62 nM and 250 nM for PKC and protein kinase A (PKA), respectively. UCN-02 (7-epi-Hydroxystaurosporine) displays cytotoxic effect on the growth of HeLa S3 cells[1][2].
Related Catalog	Signaling Pathways >> Epigenetics >> PKC Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> PKA Signaling Pathways >> Stem Cell/Wnt >> PKA Signaling Pathways >> TGF-beta/Smad >> PKC
Target	IC50: 62 nM (PKC), 250 nM (PKA)[2]
References	[1]. Takahashi I, et al. UCN-01 and UCN-02, new selective inhibitors of protein kinase C. I. Screening, producing organism and fermentation. J Antibiot (Tokyo). 1989 Apr;42(4):564-70. [2]. Takahashi I, et al. UCN-01 and UCN-02, new selective inhibitors of protein kinase C. II. Purification, physico-chemical properties, structural determination and biological activities. J Antibiot (Tokyo). 1989 Apr;42(4):571-6.

Molecular Formula	C₂₈H₂₆N₄O₄
Molecular Weight	482.537

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: ANTIBIOTIC UCN-02
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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