VU 0364439
Modify Date: 2024-01-02 18:05:42
VU 0364439 structure
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Common Name | VU 0364439 | ||
|---|---|---|---|---|
| CAS Number | 1246086-78-1 | Molecular Weight | 422.285 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C18H13Cl2N3O3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of VU 0364439VU 0364439 is a mGlu4 positive allosteric modulator (PAM), with EC50 of 19.8 nM.IC50 Value: 19.8 nM(EC50)Target: mGluRin vitro:in vivo: VU 0364439 possess less than ideal PK properties preventing their use as in vivo tools. It shows better stability in HLM (63% remaining) than RLM (2% remaining). |
| Name | N-[3-chloro-4-[(2-chlorophenyl)sulfamoyl]phenyl]pyridine-2-carboxamide |
|---|---|
| Synonym | More Synonyms |
| Description | VU 0364439 is a mGlu4 positive allosteric modulator (PAM), with EC50 of 19.8 nM.IC50 Value: 19.8 nM(EC50)Target: mGluRin vitro:in vivo: VU 0364439 possess less than ideal PK properties preventing their use as in vivo tools. It shows better stability in HLM (63% remaining) than RLM (2% remaining). |
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| Related Catalog | |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Molecular Formula | C18H13Cl2N3O3S |
| Molecular Weight | 422.285 |
| Exact Mass | 421.005463 |
| PSA | 100.03000 |
| LogP | 3.82 |
| Index of Refraction | 1.686 |
| Storage condition | -20°C |
| cc-720 |
| CS-1000 |
| 2-Pyridinecarboxamide, N-[3-chloro-4-[[(2-chlorophenyl)amino]sulfonyl]phenyl]- |
| N-{3-Chloro-4-[(2-chlorophenyl)sulfamoyl]phenyl}-2-pyridinecarboxamide |
| 2-Pyridinecarboxamide (N-[3-chloro-4-[[(2-chlorophenyl)amino]sulfonyl]phenyl] |
| VU0364439 |
| VU 0364439 |