Mito-apocynin (C2)
Modify Date: 2025-08-26 16:05:48
Mito-apocynin (C2) structure
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Common Name | Mito-apocynin (C2) | ||
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| CAS Number | 1254044-41-1 | Molecular Weight | 536.40 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H27BrNO3P | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Mito-apocynin (C2)Mito-apocynin (C2), an orally active mitochondria-targeted triphenylphosphonium (TPP)-based compound, is synthesized by conjugating the Apocynin moiety with a TPP + cation. Mito-apocynin (C2) exhibits antineuroinflammatory effect[1]. |
| Name | Mito-apocynin (C2) |
|---|
| Description | Mito-apocynin (C2), an orally active mitochondria-targeted triphenylphosphonium (TPP)-based compound, is synthesized by conjugating the Apocynin moiety with a TPP + cation. Mito-apocynin (C2) exhibits antineuroinflammatory effect[1]. |
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| Related Catalog | |
| In Vivo | Mito-apocynin (C2) (3 mg/kg; p.o.; daily for 12 days) exhibits antineuroinflammatory effect[1]. Animal Model: MPTP mice model of Parkinson’s Disease[1] Dosage: 3 mg/kg Administration: Oral gavage; daily for 12 days Result: Significantly attenuated MPTP-induced glial cell activation, proinflammatory cytokine upregulation, inducible nitric oxide synthase, and NOX2 components (gp91phox). |
| References |
| Molecular Formula | C28H27BrNO3P |
|---|---|
| Molecular Weight | 536.40 |
| InChIKey | VCBKDUGPZYICTB-UHFFFAOYSA-N |
| SMILES | COc1cc(C(=O)NCC[P+](c2ccccc2)(c2ccccc2)c2ccccc2)ccc1O.[Br-] |