AT-9010 triethylamine

Modify Date: 2024-01-06 19:43:19

AT-9010 triethylamine Structure
AT-9010 triethylamine structure
Common Name AT-9010 triethylamine
CAS Number 2648089-95-4 Molecular Weight 943.96
Density N/A Boiling Point N/A
Molecular Formula C35H77FN9O13P3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of AT-9010 triethylamine


AT-9010 triethylamine, a triphosphate active metabolite of AT-527, is a potent inhibitor of NiRAN (a function essential for viral replication). AT-9010 triethylamine can inhibit SARS-CoV-2 replication[1].

 Names

Name AT-9010 triethylamine

 AT-9010 triethylamine Biological Activity

Description AT-9010 triethylamine, a triphosphate active metabolite of AT-527, is a potent inhibitor of NiRAN (a function essential for viral replication). AT-9010 triethylamine can inhibit SARS-CoV-2 replication[1].
Related Catalog
Target

NiRAN[1]

In Vitro Substantial levels of the active triphosphate metabolite AT-9010 are formed in normal human bronchial and nasal epithelial cells incubated with 10 µM AT-511 (698 µM and 236 µM, respectively), with a half-life of at least 38 hours[1].
In Vivo SARS-CoV-2抑制剂
References

[1]. Atea Pharmaceuticals Announces Publication of Preclinical Data Highlighting Potent Activity of AT-527 Against SARS-CoV-2. BOSTON, Feb. 08, 2021. Atea Pharmaceuticals, Inc.

 Chemical & Physical Properties

Molecular Formula C35H77FN9O13P3
Molecular Weight 943.96

 Safety Information

Hazard Codes Xi