PKSI-527

Modify Date: 2025-08-26 19:10:37

PKSI-527 Structure
PKSI-527 structure
 Common Name PKSI-527
CAS Number 128837-71-8 Molecular Weight 473.99
Density N/A Boiling Point 763.1ºC at 760mmHg
Molecular Formula C25H32ClN3O4 Melting Point N/A
MSDS N/A Flash Point 415.3ºC

 Use of PKSI-527


PKSI-527 is a new, highly selective plasma kallikrein inhibitor. PKSI-527 can suppress collagen-induced arthritis (CIA) by modifying the kallikrein-kinin system[1].

 Names

Name 2-[4-[[(2S)-2-[[4-(aminomethyl)cyclohexanecarbonyl]amino]-3-phenylpropanoyl]amino]phenyl]acetic acid,hydrochloride
Synonym More Synonyms

 PKSI-527 Biological Activity

Description PKSI-527 is a new, highly selective plasma kallikrein inhibitor. PKSI-527 can suppress collagen-induced arthritis (CIA) by modifying the kallikrein-kinin system[1].
Related Catalog
References

[1]. Fujimori Y, et al. Effects of a highly selective plasma kallikrein inhibitor on collagen-induced arthritis in mice. Agents Actions. 1993 May;39(1-2):42-8.  

 Chemical & Physical Properties

Boiling Point 763.1ºC at 760mmHg
Molecular Formula C25H32ClN3O4
Molecular Weight 473.99
Flash Point 415.3ºC
Exact Mass 473.20800
PSA 125.01000
LogP 5.16040
Vapour Pressure 1.74E-24mmHg at 25°C

 Synonyms

H-Tra-L-Phe-4-carboxymethylanilide hydrochloride
Pksi 527
PKSI-0527
C25H31N3O4.HCl
t-AMCHA-Phe-p-APAA
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Chemsrc provides PKSI-527(CAS#:128837-71-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of PKSI-527 are included as well.>> amp version: PKSI-527

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