PF-04753299
Modify Date: 2024-01-10 00:39:09
PF-04753299 structure
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Common Name | PF-04753299 | ||
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| CAS Number | 1289620-49-0 | Molecular Weight | 347.42900 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C18H21NO4S | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of PF-04753299PF-04753299 is a potent and selective UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine deacetylase (LpxC) inhibitor. PF-04753299 is bactericidal for the gonococcal isolates. PF-04753299 inhibits E. coli, P. aeruginosa and K. pneumoniae strains with MIC90 values of 2 μg/ml, 4 μg/ml and 16 μg/ml, respectively. PF-04753299 is used for the study of gram-negative bacteria infection[1]. |
| Name | (2R)-4-(4-Biphenylyl)-N-hydroxy-2-methyl-2-(methylsulfonyl)butana mide |
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| Description | PF-04753299 is a potent and selective UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine deacetylase (LpxC) inhibitor. PF-04753299 is bactericidal for the gonococcal isolates. PF-04753299 inhibits E. coli, P. aeruginosa and K. pneumoniae strains with MIC90 values of 2 μg/ml, 4 μg/ml and 16 μg/ml, respectively. PF-04753299 is used for the study of gram-negative bacteria infection[1]. |
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| Related Catalog | |
| Target |
IC50: bacterial[1] |
| References |
| Molecular Formula | C18H21NO4S |
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| Molecular Weight | 347.42900 |
| Exact Mass | 347.11900 |
| PSA | 95.34000 |
| LogP | 4.51600 |
| RIDADR | NONH for all modes of transport |
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