PF-04753299

Modify Date: 2024-01-10 00:39:09

PF-04753299 structure	Common Name	PF-04753299
	CAS Number	1289620-49-0	Molecular Weight	347.42900
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₈H₂₁NO₄S	Melting Point	N/A
	MSDS	USA	Flash Point	N/A

Use of PF-04753299

PF-04753299 is a potent and selective UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine deacetylase (LpxC) inhibitor. PF-04753299 is bactericidal for the gonococcal isolates. PF-04753299 inhibits E. coli, P. aeruginosa and K. pneumoniae strains with MIC90 values of 2 μg/ml, 4 μg/ml and 16 μg/ml, respectively. PF-04753299 is used for the study of gram-negative bacteria infection[1].

Name	(2R)-4-(4-Biphenylyl)-N-hydroxy-2-methyl-2-(methylsulfonyl)butana mide

Description	PF-04753299 is a potent and selective UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine deacetylase (LpxC) inhibitor. PF-04753299 is bactericidal for the gonococcal isolates. PF-04753299 inhibits E. coli, P. aeruginosa and K. pneumoniae strains with MIC90 values of 2 μg/ml, 4 μg/ml and 16 μg/ml, respectively. PF-04753299 is used for the study of gram-negative bacteria infection[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	IC50: bacterial[1]
References	[1]. Constance M John, et al. Treatment of human challenge and MDR strains of Neisseria gonorrhoeae with LpxC inhibitors. J Antimicrob Chemother. 2018 Aug 1;73(8):2064-2071.

Molecular Formula	C₁₈H₂₁NO₄S
Molecular Weight	347.42900
Exact Mass	347.11900
PSA	95.34000
LogP	4.51600

RIDADR	NONH for all modes of transport

DC Chemicals Limited
China
Product Name: PF-04753299
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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