Lipoamide-PEG3-Mal

Modify Date: 2024-01-09 18:56:56

Lipoamide-PEG3-Mal Structure
Lipoamide-PEG3-Mal structure
Common Name Lipoamide-PEG3-Mal
CAS Number 1314378-19-2 Molecular Weight 559.739
Density 1.2±0.1 g/cm3 Boiling Point 786.9±60.0 °C at 760 mmHg
Molecular Formula C25H41N3O7S2 Melting Point N/A
MSDS N/A Flash Point 429.7±32.9 °C

 Use of Lipoamide-PEG3-Mal


Lipoamide-PEG3-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Lipoamide-PEG3-Mal
Synonym More Synonyms

 Lipoamide-PEG3-Mal Biological Activity

Description Lipoamide-PEG3-Mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 786.9±60.0 °C at 760 mmHg
Molecular Formula C25H41N3O7S2
Molecular Weight 559.739
Flash Point 429.7±32.9 °C
Exact Mass 559.238586
LogP 0.28
Vapour Pressure 0.0±2.7 mmHg at 25°C
Index of Refraction 1.544

 Synonyms

LIPOAMIDE-PEG3-NH-MAL
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