Azido-PEG8-CH2CO2H

Modify Date: 2024-01-22 10:05:12

Azido-PEG8-CH2CO2H Structure
Azido-PEG8-CH2CO2H structure
Common Name Azido-PEG8-CH2CO2H
CAS Number 1343472-07-0 Molecular Weight 453.485
Density N/A Boiling Point N/A
Molecular Formula C18H35N3O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG8-CH2CO2H


N3-PEG8-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

 Names

Name N3-PEG8-CH2COOH
Synonym More Synonyms

 Azido-PEG8-CH2CO2H Biological Activity

Description N3-PEG8-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Steinmetz NF, et al. Intravital imaging of human prostate cancer using viral nanoparticles targeted to gastrin-releasing Peptide receptors. Small. 2011 Jun 20;7(12):1664-72.

 Chemical & Physical Properties

Molecular Formula C18H35N3O10
Molecular Weight 453.485
Exact Mass 453.232239
LogP -2.88
Storage condition 2-8°C

 Synonyms

AZIDE-PEG8-CH2COOH
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