Azido-PEG8-CH2CO2-PFP

Modify Date: 2025-08-27 07:54:09

Azido-PEG8-CH2CO2-PFP Structure
Azido-PEG8-CH2CO2-PFP structure
Common Name Azido-PEG8-CH2CO2-PFP
CAS Number 2182601-80-3 Molecular Weight 619.53
Density N/A Boiling Point N/A
Molecular Formula C24H34F5N3O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azido-PEG8-CH2CO2-PFP


Azido-PEG8-CH2COO-PFP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azido-PEG8-CH2COO-PFP

 Azido-PEG8-CH2CO2-PFP Biological Activity

Description Azido-PEG8-CH2COO-PFP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C24H34F5N3O10
Molecular Weight 619.53
InChIKey JAGMBOXHJXUFJS-UHFFFAOYSA-N
SMILES [N-]=[N+]=NCCOCCOCCOCCOCCOCCOCCOCCOCC(=O)Oc1c(F)c(F)c(F)c(F)c1F
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