m-PEG5-CH2CH2COOH

Modify Date: 2024-01-16 11:58:38

m-PEG5-CH2CH2COOH Structure
m-PEG5-CH2CH2COOH structure
Common Name m-PEG5-CH2CH2COOH
CAS Number 1347750-72-4 Molecular Weight 324.367
Density 1.1±0.1 g/cm3 Boiling Point 431.5±45.0 °C at 760 mmHg
Molecular Formula C14H28O8 Melting Point N/A
MSDS N/A Flash Point 148.5±22.2 °C

 Use of m-PEG5-CH2CH2COOH


m-PEG5-CH2CH2COOH is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs.

 Names

Name 2,5,8,11,14,17-Hexaoxaicosan-20-oic acid
Synonym More Synonyms

 m-PEG5-CH2CH2COOH Biological Activity

Description m-PEG5-CH2CH2COOH is a PEG-based based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Parva Yogeshchandra Purohit, et al. Prodrugs of fulvestrant. WO2019224790A2.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 431.5±45.0 °C at 760 mmHg
Molecular Formula C14H28O8
Molecular Weight 324.367
Flash Point 148.5±22.2 °C
Exact Mass 324.178406
LogP -2.07
Vapour Pressure 0.0±2.2 mmHg at 25°C
Index of Refraction 1.452

 Safety Information

Hazard Codes Xi

 Synonyms

2,5,8,11,14,17-Hexaoxaicosan-20-oic acid
MFCD20926383
2,5,8,11,14,17-Hexaoxaeicosan-20-oic acid
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