AZD-3463

Modify Date: 2024-01-07 15:52:52

AZD-3463 Structure
AZD-3463 structure
Common Name AZD-3463
CAS Number 1356962-20-3 Molecular Weight 448.948
Density 1.3±0.1 g/cm3 Boiling Point 723.6±70.0 °C at 760 mmHg
Molecular Formula C24H25ClN6O Melting Point N/A
MSDS N/A Flash Point 391.4±35.7 °C

 Use of AZD-3463


AZD-3463 is an ALK/IGF1R inhibitor which overcomes multiple mechanisms of acquired resistance to crizotinib.IC50 Value:Target: ALK/IGF1R

 Names

Name N-[4-(4-aminopiperidin-1-yl)-2-methoxyphenyl]-5-chloro-4-(1H-indol-3-yl)pyrimidin-2-amine
Synonym More Synonyms

 AZD-3463 Biological Activity

Description AZD-3463 is an ALK/IGF1R inhibitor which overcomes multiple mechanisms of acquired resistance to crizotinib.IC50 Value:Target: ALK/IGF1R
Related Catalog

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 723.6±70.0 °C at 760 mmHg
Molecular Formula C24H25ClN6O
Molecular Weight 448.948
Flash Point 391.4±35.7 °C
Exact Mass 448.177826
PSA 92.09000
LogP 3.11
Vapour Pressure 0.0±2.3 mmHg at 25°C
Index of Refraction 1.693
Storage condition -20℃

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

ALK/IGF1R inhibitor||AZD3463|AZD 3463
N-[4-(4-Amino-1-piperidinyl)-2-methoxyphenyl]-5-chloro-4-(1H-indol-3-yl)-2-pyrimidinamine
AZD3463
2-Pyrimidinamine, N-[4-(4-amino-1-piperidinyl)-2-methoxyphenyl]-5-chloro-4-(1H-indol-3-yl)-
ALK/IGF1R inhibitor
S7106
N-(4-(4-aminopiperidin-1-yl)-2-methoxyphenyl)-5-chloro-4-(1H-indol-3-yl)pyrimidin-2-amine
CS-1382
AZD-3463
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Price: $125/10mM*1mLinDMSO

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