TAT 14TFA

Modify Date: 2025-08-27 07:50:31

TAT 14TFA Structure
TAT 14TFA structure
Common Name TAT 14TFA
CAS Number 1362661-34-4 Molecular Weight 3173.59
Density N/A Boiling Point N/A
Molecular Formula C137H230N48O39 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TAT 14TFA


TAT-14 is a 14-mer peptide that acts as Nrf2 activator with an anti-inflammatory effect. TAT-14 has no effect on Nrf2 mRNA expression, but increases Nrf2 protein level due to targeting the Nrf2 binding site on Keap1[1].

 Names

Name TAT-14

 TAT 14TFA Biological Activity

Description TAT-14 is a 14-mer peptide that acts as Nrf2 activator with an anti-inflammatory effect. TAT-14 has no effect on Nrf2 mRNA expression, but increases Nrf2 protein level due to targeting the Nrf2 binding site on Keap1[1].
Related Catalog
Target

IC50: Nrf2[1]

References

[1]. Richard Steel, et al. Anti-inflammatory Effect of a Cell-Penetrating Peptide Targeting the Nrf2/Keap1 Interaction. ACS Med Chem Lett. 2012 May 10;3(5):407-410.

 Chemical & Physical Properties

Molecular Formula C137H230N48O39
Molecular Weight 3173.59
InChIKey NBFQPSCRGQGZEP-YBKRDZSWSA-N
SMILES CCC(C)C(NC(=O)C1CCCN1C(=O)C(CC(C)C)NC(=O)C(Cc1ccccc1)NC(=O)C(CCC(=O)O)NC(=O)CNC(=O)C(NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CCC(N)=O)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(N)=O)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(CCCNC(=N)N)NC(=O)CNC(=O)C(N)Cc1ccc(O)cc1)C(C)O)C(=O)NC(CCC(N)=O)C(=O)O
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