LTD4 antagonist 1

Modify Date: 2025-10-22 18:01:36

LTD4 antagonist 1 structure	Common Name	LTD4 antagonist 1
	CAS Number	136564-67-5	Molecular Weight	615.66
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₃₁H₃₂F₃N₃O₅S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of LTD4 antagonist 1

LTD4 antagonist 1 is a potent, orally active antagonist of leukotriene D4 (LTD4) with a Ki of 0.57 nM.

Name	LTD4 antagonist 1

Description	LTD4 antagonist 1 is a potent, orally active antagonist of leukotriene D4 (LTD4) with a Ki of 0.57 nM.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Leukotriene Receptor Research Areas >> Inflammation/Immunology
Target	LTD4:0.57 nM (Ki)
In Vitro	LTD4 antagonist 1 (Compound 38b) exhibits a Ki of 0.57 nM for displacement of [3H]LTD4 on guinea pig lung membranes, a pKB of 9.93±0.14 versus LTE4 on guinea pig trachea[1].
In Vivo	LTD4 antagonist 1 (Compound 38b) exhibits a po ED50/iv ED50 of 1.44 and 0.036 μmol/kg in LTD4-induced bronchoconstriction in guinea pigs[1].
References	[1]. Robert T. Jacobs, et al. Synthesis, Structure-Activity Relationships, and Pharmacological Evaluation of a Series of Fluorinated 3-Benzyl-5-Indolecarboxamides: Identification of 4-[[5-[((2R)-2-Methyl-4,4,4-trifluorobutyl)carbamoyl]-1-methylindol-3-yl]methyl]-3methoxy-N-[(2-methylphenyl)sulfonyl]benzamide, a Potent, Orally Active Antagonist of Leukotrienes D4 and E4. Journal of Medicinal Chemistry (1994), 37(9), 1282-97.

Molecular Formula	C₃₁H₃₂F₃N₃O₅S
Molecular Weight	615.66

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: LTD4 antagonist 1
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Get all suppliers and price by the below link:

LTD4 antagonist 1 suppliers

Price: $1536/1mg

Reference only. check more LTD4 antagonist 1 price