ARN 077

Modify Date: 2024-01-28 10:12:51

ARN 077 structure	Common Name	ARN 077
	CAS Number	1373625-34-3	Molecular Weight	291.34
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₆H₂₁NO₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ARN 077

ARN 077 is a potent and selective N-acylethanolamine acid amidase (NAAA) inhibitor with an IC50 of 7 nM for human NAAA[1]. ARN 077 significantly increases palmitoyl ethanolamine (PEA) levels within the CNS and has broad antinociceptive activity in mice and rats[2].

Name	ARN 077

Description	ARN 077 is a potent and selective N-acylethanolamine acid amidase (NAAA) inhibitor with an IC50 of 7 nM for human NAAA[1]. ARN 077 significantly increases palmitoyl ethanolamine (PEA) levels within the CNS and has broad antinociceptive activity in mice and rats[2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
Target	IC50: 7 nM (human NAAA)[1].
References	[1]. Sasso O, et al. Antinociceptive effects of the N-acylethanolamine acid amidase inhibitor ARN077 in rodent pain models. Pain. 2013 Mar;154(3):350-60. [2]. Davis MP, et al. Cannabinoids in pain management: CB1, CB2 and non-classic receptor ligands. Expert Opin Investig Drugs. 2014 Aug;23(8):1123-40.

Molecular Formula	C₁₆H₂₁NO₄
Molecular Weight	291.34

DC Chemicals Limited
China
Product Name: ARN 077
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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