ARN-3236
Modify Date: 2024-01-11 15:52:23
ARN-3236 structure
|
Common Name | ARN-3236 | ||
|---|---|---|---|---|
| CAS Number | 1613710-01-2 | Molecular Weight | 336.41 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H16N2O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of ARN-3236ARN-3236 is an oral active and selective inhibitor of salt-inducible kinase 2 (SIK2) (IC50 <1 nM), with activity in inhibiting growth and enhancing paclitaxel sensitivity in cultures and xenografts of ovarian cancer cell lines[1][2]. |
| Name | ARN-3236 |
|---|---|
| Synonym | More Synonyms |
| Description | ARN-3236 is an oral active and selective inhibitor of salt-inducible kinase 2 (SIK2) (IC50 <1 nM), with activity in inhibiting growth and enhancing paclitaxel sensitivity in cultures and xenografts of ovarian cancer cell lines[1][2]. |
|---|---|
| Related Catalog | |
| Target |
SIK2:<1 nM (IC50) SIK1:21.63 nM (IC50) SIK3:6.63 nM (IC50) |
| References |
| Molecular Formula | C19H16N2O2S |
|---|---|
| Molecular Weight | 336.41 |
| Storage condition | 2-8℃ |
| 3-(2,4-DIMETHOXYPHENYL)-4-(THIOPHEN-3-YL)-1H-PYRROLO[2,3-B]PYRIDINE |