Bisindolylmaleimide III

Modify Date: 2024-01-16 13:41:41

Bisindolylmaleimide III structure	Common Name	Bisindolylmaleimide III
	CAS Number	137592-43-9	Molecular Weight	384.43
	Density	1.4±0.1 g/cm3	Boiling Point	708.7±60.0 °C at 760 mmHg
	Molecular Formula	C₂₃H₂₀N₄O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	382.4±32.9 °C

Use of Bisindolylmaleimide III

Bisindolylmaleimide III is a potent and selective inhibitor of protein kinase C (PKC). Bisindolylmaleimide III selectively interacts with either PKCα or ribosomal S6 protein kinase 1 after activation of these kinases[1].

Name	Bisindolylmaleimide III
Synonym	More Synonyms

Description	Bisindolylmaleimide III is a potent and selective inhibitor of protein kinase C (PKC). Bisindolylmaleimide III selectively interacts with either PKCα or ribosomal S6 protein kinase 1 after activation of these kinases[1].
Related Catalog	Signaling Pathways >> Epigenetics >> PKC Research Areas >> Cancer Signaling Pathways >> TGF-beta/Smad >> PKC
Target	PKCα
References	[1]. Brehmer D, et, al. Proteome-wide identification of cellular targets affected by bisindolylmaleimide-type protein kinase C inhibitors. Mol Cell Proteomics. 2004 May;3(5):490-500. [2]. Saito Y, et, al. Role of ecto-kinase in phorbol ester-enhanced growth hormone-binding protein release from human IM-9 cells. Mol Cell Endocrinol. 1999 Jun 25;152(1-2):65-72.

Density	1.4±0.1 g/cm3
Boiling Point	708.7±60.0 °C at 760 mmHg
Molecular Formula	C₂₃H₂₀N₄O₂
Molecular Weight	384.43
Flash Point	382.4±32.9 °C
Exact Mass	384.158630
PSA	92.91000
LogP	3.15
Vapour Pressure	0.0±2.3 mmHg at 25°C
Index of Refraction	1.739

1H-Pyrrole-2,5-dione, 3-[1-(3-aminopropyl)-1H-indol-3-yl]-4-(1H-indol-3-yl)-

3-[1-(3-Aminopropyl)-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: BISINDOLYLMALEIMIDE III
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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