IDO-IN-6

Modify Date: 2024-01-14 08:40:15

IDO-IN-6 Structure
IDO-IN-6 structure
Common Name IDO-IN-6
CAS Number 1402837-76-6 Molecular Weight 316.370
Density 1.4±0.1 g/cm3 Boiling Point 555.4±35.0 °C at 760 mmHg
Molecular Formula C18H21FN2O2 Melting Point N/A
MSDS N/A Flash Point 289.7±25.9 °C

 Use of IDO-IN-6


IDO-IN-6 (NLG-1486) is an indoleamine 2,3-dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, Compound 1486, has an IC50 of <1 μM.

 Names

Name IDO-IN-6
Synonym More Synonyms

 IDO-IN-6 Biological Activity

Description IDO-IN-6 (NLG-1486) is an indoleamine 2,3-dioxygenase (IDO) inhibitor extracted from patent WO WO2012142237A1, Compound 1486, has an IC50 of <1 μM.
Related Catalog
Target

IDO:1 μM (IC50)

In Vitro IDO-IN-6 (Compound 1486) is an indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of <1 μM (this is the concentration of IDO-IN-6 at which inhibits 50% of enzymatic activity using recombinant human IDO)[1].
References

[1]. Mautino, et al. Preparation of fused imidazole derivatives as IDO inhibitors. From PCT Int. Appl. (2012), 20121018.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 555.4±35.0 °C at 760 mmHg
Molecular Formula C18H21FN2O2
Molecular Weight 316.370
Flash Point 289.7±25.9 °C
Exact Mass 316.158691
LogP 1.28
Vapour Pressure 0.0±1.6 mmHg at 25°C
Index of Refraction 1.683
Storage condition 2-8℃

 Synonyms

5H-Imidazo[5,1-a]isoindole-5-ethanol, 6-fluoro-α-(trans-4-hydroxycyclohexyl)-, (αS,5S)-
trans-4-{(1S)-2-[(5S)-6-Fluoro-5H-imidazo[5,1-a]isoindol-5-yl]-1-hydroxyethyl}cyclohexanol