IDO-IN-1

Modify Date: 2024-01-14 15:42:02

Use of IDO-IN-1

IDO-IN-1 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 59 nM.

Name	4-Amino-N-(3-bromo-4-fluorophenyl)-N'-hydroxy-1,2,5-oxadiazole-3-carboximidamide
Synonym	More Synonyms

Description	IDO-IN-1 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 59 nM.
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Indoleamine 2,3-Dioxygenase (IDO) Research Areas >> Cancer
Target	IDO:59 nM (IC50) IDO:12 nM (IC50, in HeLa cell)
In Vitro	IDO-IN-1 (Compound 5m) is a potent (HeLa IC50=12 nM) inhibitor of IDO[1].
References	[1]. Yue EW, et al. Discovery of potent competitive inhibitors of indoleamine 2,3-dioxygenase with in vivo pharmacodynamic activity and efficacy in a mouse melanoma model. J Med Chem. 2009 Dec 10;52(23):7364-7.

IDO-IN-1

4-amino-N(3-bromo-4-fluorophenyl)-N-hydroxy-

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Price: $480/10mM*1mLinDMSO

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