JW 642 structure
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Common Name | JW 642 | ||
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CAS Number | 1416133-89-5 | Molecular Weight | 462.385 | |
Density | 1.4±0.1 g/cm3 | Boiling Point | 432.9±45.0 °C at 760 mmHg | |
Molecular Formula | C21H20F6N2O3 | Melting Point | N/A | |
MSDS | N/A | Flash Point | 215.6±28.7 °C |
Use of JW 642JW 642 is a potent inhibitor of monoacylglycerol lipase (MAGL) that displays IC50 values of 7.6, 14, and 3.7 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively.IC50 value: 7.6/14/3.7 nM(mouse/rat/human MAGL) [1]Target: MAGL inhibitorJW 642 is selective for MAGL, requiring much higher concentrations to effectively inhibit fatty acid amide hydrolase activity (IC50s = 31, 14, and 20.6 μM for mouse, rat, and human brain membranes, respectively). |
Name | 1,1,1,3,3,3-Hexafluoro-2-propanyl 4-(3-phenoxybenzyl)-1-piperazin ecarboxylate |
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Synonym | More Synonyms |
Description | JW 642 is a potent inhibitor of monoacylglycerol lipase (MAGL) that displays IC50 values of 7.6, 14, and 3.7 nM for inhibition of MAGL in mouse, rat, and human brain membranes, respectively.IC50 value: 7.6/14/3.7 nM(mouse/rat/human MAGL) [1]Target: MAGL inhibitorJW 642 is selective for MAGL, requiring much higher concentrations to effectively inhibit fatty acid amide hydrolase activity (IC50s = 31, 14, and 20.6 μM for mouse, rat, and human brain membranes, respectively). |
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Related Catalog | |
References |
Density | 1.4±0.1 g/cm3 |
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Boiling Point | 432.9±45.0 °C at 760 mmHg |
Molecular Formula | C21H20F6N2O3 |
Molecular Weight | 462.385 |
Flash Point | 215.6±28.7 °C |
Exact Mass | 462.137817 |
PSA | 42.01000 |
LogP | 6.43 |
Vapour Pressure | 0.0±1.0 mmHg at 25°C |
Index of Refraction | 1.511 |
Storage condition | 2-8℃ |
1,1,1,3,3,3-Hexafluoro-2-propanyl 4-(3-phenoxybenzyl)-1-piperazinecarboxylate |
1,1,1,3,3,3-hexafluoroisopropyl cyanoacetate |
1-Piperazinecarboxylic acid, 4-[(3-phenoxyphenyl)methyl]-, 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ester |
JW 642 |
JW-642 |