RORγt-IN-9a

Modify Date: 2025-09-10 19:07:02

RORγt-IN-9a Structure
RORγt-IN-9a structure
Common Name RORγt-IN-9a
CAS Number 1426803-07-7 Molecular Weight 518.328
Density N/A Boiling Point N/A
Molecular Formula C22H16Cl2F3NO4S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of RORγt-IN-9a


A potent, selective, CNS penetrant, orally bioavailable RORγt with pIC50 of 8.3 in FRET assays; has TH17 pEC50 of 7.3, demonstrates excellent in vivo efficacy in EAE mice.

 Names

Name RORγt-IN-9a

 RORγt-IN-9a Biological Activity

Description A potent, selective, CNS penetrant, orally bioavailable RORγt with pIC50 of 8.3 in FRET assays; has TH17 pEC50 of 7.3, demonstrates excellent in vivo efficacy in EAE mice.
References References 1. Wang Y, et al. ACS Med Chem Lett. 2015 May 26;6(7):787-92. View Related Products by Target ROR

 Chemical & Physical Properties

Molecular Formula C22H16Cl2F3NO4S
Molecular Weight 518.328
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