Azide-PEG3-Desthiobiotin

Modify Date: 2024-01-09 20:23:59

Azide-PEG3-Desthiobiotin Structure
Azide-PEG3-Desthiobiotin structure
Common Name Azide-PEG3-Desthiobiotin
CAS Number 1426828-06-9 Molecular Weight 414.51
Density N/A Boiling Point N/A
Molecular Formula C18H34N6O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Azide-PEG3-Desthiobiotin


Azide-PEG3-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Azide-PEG3-Desthiobiotin

 Azide-PEG3-Desthiobiotin Biological Activity

Description Azide-PEG3-Desthiobiotin is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C18H34N6O5
Molecular Weight 414.51