CCG-203586
Modify Date: 2024-04-02 19:06:07
CCG-203586 structure
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Common Name | CCG-203586 | ||
|---|---|---|---|---|
| CAS Number | 1430611-24-7 | Molecular Weight | 436.552 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H32N2O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CCG-203586A potent, CNS-active Glucosylceramide synthase (GCS) inhibitor with IC50 of 27 nM; inhibits GlcCer production in whole wild-type MDCKII cells with IC50 of 15.3 nM, has little to no apparent recognition by MDR1; significantly and dose-dependently decreases brain glucosylceramide content after intraperitoneal administration in mice. |
| Name | CCG-203586 |
|---|
| Description | A potent, CNS-active Glucosylceramide synthase (GCS) inhibitor with IC50 of 27 nM; inhibits GlcCer production in whole wild-type MDCKII cells with IC50 of 15.3 nM, has little to no apparent recognition by MDR1; significantly and dose-dependently decreases brain glucosylceramide content after intraperitoneal administration in mice. |
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| References | References 1. Larsen SD, et al. J Lipid Res. 2012 Feb;53(2):282-91. 2. Arthur JR, et al. Neurochem Res. 2013 Apr;38(4):866-75. View Related Products by Target Other Targets |
| Molecular Formula | C26H32N2O4 |
|---|---|
| Molecular Weight | 436.552 |