Sophocarpine structure
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Common Name | Sophocarpine | ||
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CAS Number | 145572-44-7 | Molecular Weight | 246.348 | |
Density | 1.2±0.1 g/cm3 | Boiling Point | 425.4±45.0 °C at 760 mmHg | |
Molecular Formula | C15H22N2O | Melting Point | N/A | |
MSDS | N/A | Flash Point | 194.0±21.1 °C |
Use of SophocarpineSophocarpine (monohydrate) is one of the significant alkaloid extracted from the traditional herb medicine Sophora flavescens which has many pharmacological properties such as anti-virus, anti-tumor, anti-inflammatory. Sophocarpine (monohydrate) significantly inhibits the growth of gastric cancer (GC) cells through multiple mechanisms such as induction of autophagy, activation of cell apoptosis and down-regulation of cell survival PI3K/AKT signaling pathway. Sophocarpine (monohydrate) has been demonstrated to have anti-tumor activity in various cancer cells, including hepatocellular carcinoma, prostate cancer and colorectal cancer[1]. |
Name | 13,14-Didehydromatridin-15-one |
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Synonym | More Synonyms |
Description | Sophocarpine (monohydrate) is one of the significant alkaloid extracted from the traditional herb medicine Sophora flavescens which has many pharmacological properties such as anti-virus, anti-tumor, anti-inflammatory. Sophocarpine (monohydrate) significantly inhibits the growth of gastric cancer (GC) cells through multiple mechanisms such as induction of autophagy, activation of cell apoptosis and down-regulation of cell survival PI3K/AKT signaling pathway. Sophocarpine (monohydrate) has been demonstrated to have anti-tumor activity in various cancer cells, including hepatocellular carcinoma, prostate cancer and colorectal cancer[1]. |
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Related Catalog | |
Target |
PI3K Akt |
References |
Density | 1.2±0.1 g/cm3 |
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Boiling Point | 425.4±45.0 °C at 760 mmHg |
Molecular Formula | C15H22N2O |
Molecular Weight | 246.348 |
Flash Point | 194.0±21.1 °C |
Exact Mass | 246.173218 |
PSA | 23.55000 |
LogP | 1.37 |
Vapour Pressure | 0.0±1.0 mmHg at 25°C |
Index of Refraction | 1.603 |
1H,5H,10H-Dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one, 2,3,6,7,7a,8,13,13a,13b,13c-decahydro-, (7aS,13aR,13bR,13cS)- |
Sophocarpine |
Matridine-13-ene-15-one |
Matridin-15-one, 13,14-didehydro- |
Matridin-15-one, 13,14-didehydro- (9CI) |
13,14-Didehydromatridin-15-one |