MS-PEG4-THP

Modify Date: 2024-01-11 22:16:28

MS-PEG4-THP Structure
MS-PEG4-THP structure
Common Name MS-PEG4-THP
CAS Number 145927-73-7 Molecular Weight 356.43
Density N/A Boiling Point N/A
Molecular Formula C14H28O8S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MS-PEG4-THP


MS-PEG4-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Mes-PEG5- THP
Synonym More Synonyms

 MS-PEG4-THP Biological Activity

Description MS-PEG4-THP is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C14H28O8S
Molecular Weight 356.43

 Synonyms

MFCD29049413